Evidence map›Paper›PMID 33164898›Full record

ArticleJMIR research protocols2020

Artificial Intelligence-Powered Smartphone App to Facilitate Medication Adherence: Protocol for a Human Factors Design Study.

Don Roosan, Jay Chok, Mazharul Karim, Anandi V Law, Andrius Baskys, Angela Hwang, Moom R Roosan

Open access · goldAbstract read
In one paragraph

Article in JMIR research protocols, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
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  9. Artificial Intelligent Context-Aware Machine-Learning Tool to Detect Adverse Drug Events from Social Media Platforms.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2022
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  14. Persistence as a Robust Indicator of Medication Adherence-Related Quality and Performance.International journal of environmental research and public health · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Don Roosan *Department of Pharmacy Practice and Administration, College of Pharmacy, Western University of Health Sciences, Pomona, CA, United States.ORCID https://orcid.org/0000-0003-2482-6053
Jay ChokSchool of Applied Life Sciences, Keck Graduate Institute, Claremont Colleges, Claremeont, CA, United States.ORCID https://orcid.org/0000-0002-2082-0079
Mazharul KarimDepartment of Pharmacy Practice and Administration, College of Pharmacy, Western University of Health Sciences, Pomona, CA, United States.ORCID https://orcid.org/0000-0003-4412-1819
Anandi V LawDepartment of Pharmacy Practice and Administration, College of Pharmacy, Western University of Health Sciences, Pomona, CA, United States.ORCID https://orcid.org/0000-0002-9697-2757
Andrius BaskysGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA, United States.ORCID https://orcid.org/0000-0001-6280-5005
Angela HwangDepartment of Pharmacy Practice and Administration, College of Pharmacy, Western University of Health Sciences, Pomona, CA, United States.ORCID https://orcid.org/0000-0001-7937-3333
Moom R Roosan *Department of Pharmacy Practice, School of Pharmacy, Chapman University, Irvine, CA, United States.ORCID https://orcid.org/0000-0002-5318-5120
Western University of Health Sciences · USChapman University · USClaremont Colleges · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedication Guides consisting of crucial interactions and side effects are extensive and complex. Due to the exhaustive information, patients do not retain the necessary medication information, which can result in hospitalizations and medication nonadherence. A gap exists in understanding patients' cognition of managing complex medication information. However, advancements in technology and artificial intelligence (AI) allow us to understand patient cognitive processes to design an app to better provide important medication information to patients.

objectiveOur objective is to improve the design of an innovative AI- and human factor-based interface that supports patients' medication information comprehension that could potentially improve medication adherence.

methodsThis study has three aims. Aim 1 has three phases: (1) an observational study to understand patient perception of fear and biases regarding medication information, (2) an eye-tracking study to understand the attention locus for medication information, and (3) a psychological refractory period (PRP) paradigm study to understand functionalities. Observational data will be collected, such as audio and video recordings, gaze mapping, and time from PRP. A total of 50 patients, aged 18-65 years, who started at least one new medication, for which we developed visualization information, and who have a cognitive status of 34 during cognitive screening using the TICS-M test and health literacy level will be included in this aim of the study. In Aim 2, we will iteratively design and evaluate an AI-powered medication information visualization interface as a smartphone app with the knowledge gained from each component of Aim 1. The interface will be assessed through two usability surveys. A total of 300 patients, aged 18-65 years, with diabetes, cardiovascular diseases, or mental health disorders, will be recruited for the surveys. Data from the surveys will be analyzed through exploratory factor analysis. In Aim 3, in order to test the prototype, there will be a two-arm study design. This aim will include 900 patients, aged 18-65 years, with internet access, without any cognitive impairment, and with at least two medications. Patients will be sequentially randomized. Three surveys will be used to assess the primary outcome of medication information comprehension and the secondary outcome of medication adherence at 12 weeks.

resultsPreliminary data collection will be conducted in 2021, and results are expected to be published in 2022.

conclusionsThis study will lead the future of AI-based, innovative, digital interface design and aid in improving medication comprehension, which may improve medication adherence. The results from this study will also open up future research opportunities in understanding how patients manage complex medication information and will inform the format and design for innovative, AI-powered digital interfaces for Medication Guides. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/21659.

Indexed as

artificial intelligencecomplex medication informationmachine learningmedication adherencemobile phonepatient cognitionsmartphone app

Identifiers

PMID33164898
PMCPMC7683257
OpenAlexW3100612557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.