ArticleBrain, behavior, & immunity - health2020
Cytokine storm induced new onset depression in patients with COVID-19. A new look into the association between depression and cytokines -two case reports.
Article in Brain, behavior, & immunity - health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed, 45 citations in OpenAlex.
- Severity of SARS-CoV-2 infection increases the risk of generalized anxiety disorder, major depressive disorder, and post-traumatic stress disorder in COVID-19 survivors: a prospective longitudinal cohort study.Brain, behavior, & immunity - health · 2026Article
- Lessons from irritable bowel syndrome: potential for understanding and managing post-COVID.Frontiers in immunology · 2026Review
- An Overview of Depression Pathogenesis: Prevailing Hypotheses and Associated Neurobiological Underpinnings Primarily Evidenced by Rodent Studies.Depression and anxiety · 2026Review
- Post-COVID-19 Syndrome as Described by Patients: A Qualitative Study.Healthcare (Basel, Switzerland) · 2025Article
- Unraveling the Role of the Blood-Brain Barrier in the Pathophysiology of Depression: Recent Advances and Future Perspectives.Molecular neurobiology · 2024Review
- Exploring common pathogenic association between Epstein Barr virus infection and long-COVID by integrating RNA-Seq and molecular dynamics simulations.Frontiers in immunology · 2024Article
- Long COVID-19 Pathophysiology: What Do We Know So Far?Microorganisms · 2023Review
- Post-COVID Interstitial Lung Disease and Other Lung Sequelae.Clinics in chest medicine · 2023Review
- Impact of Rehabilitation on Physical and Neuropsychological Health of Patients Who Acquired COVID-19 in the Workplace.International journal of environmental research and public health · 2023Observational
- Depression, Anxiety, and Quality of Life in Patients Treated with Single Infusion Tocilizumab for COVID-19: A Follow-up, Controlled Study.Indian journal of psychological medicine · 2023Article
- Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options.International immunopharmacology · 2022Review
- Global prevalence of chronic fatigue syndrome among long COVID-19 patients: A systematic review and meta-analysis.BioPsychoSocial medicine · 2022Article
- The Relationship between Mental Disorders and the COVID-19 Pandemic-Course, Risk Factors, and Potential Consequences.International journal of environmental research and public health · 2022Review
- On Patterns of Neuropsychiatric Symptoms in Patients With COVID-19: A Systematic Review of Case Reports.Cureus · 2022Review
- Long COVID: a narrative review of the clinical aftermaths of COVID-19 with a focus on the putative pathophysiology and aspects of physical activity.Oxford open immunology · 2022Review
- Correction of Psychoemotional Disorders and Short-Term Prognosis in Patients with COVID-19.Neuroscience and behavioral physiology · 2022Article
- The contribution of gut-brain axis to development of neurological symptoms in COVID-19 recovered patients: A hypothesis and review of literature.Frontiers in cellular and infection microbiology · 2022Review
- Review
- Depressive and Neurocognitive Disorders in the Context of the Inflammatory Background of COVID-19.Life (Basel, Switzerland) · 2021Review
- The Impact of the COVID-19 Pandemic on Mental Disorders. A Critical Review.International journal of environmental research and public health · 2021Review
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDepression appears to be a common complication in patients during and post-COVID-19 infection. Understanding the mechanism of action of cytokines such as interleukin-6, interleukin-10 and others in depression and in cytokine storm syndrome, the core component of COVID- 19, could shine a new light on future treatment options for both disorders.
objectiveThis review demonstrates the role of interleukins in COVID-19 pathogenesis and their role in depression.
resultsWe described cases we have treated as an example for the dual role interleukins have in COVID-19 infection and depression and reviewed approximately 70 articles focusing on the role of interleukins in cytokine storm syndrome and depression.
conclusionThis review highlights the key features of cytokines in both diseases. As the scientific community has more time to recover and process the effect of the current pandemic, we believe that additional research will pave the way to diverse pathways to treat depression in these patient and others.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.