ArticleIJU case reports2020
Successful treatment of recurrent small cell carcinoma of urinary bladder with pembrolizumab.
Article in IJU case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 11 citations in OpenAlex.
- Mixed carcinoma transdifferentiation of bladder urothelial carcinoma after chemotherapy: A case report.Oncology letters · 2026Article
- Prognostic and predictive factors of immune checkpoint inhibitor therapy in urinary bladder cancer.Pathology oncology research : POR · 2026Review
- Small cell bladder carcinoma with a high tumor mutational burden responding to sequential cisplatin-etoposide and pembrolizumab: a case report.International cancer conference journal · 2025Article
- A Case of Small Cell Carcinoma of Bladder With Significant Tumor Reduction Following Combination Chemotherapy and Radiation Therapy.IJU case reports · 2025Article
- A phase II study of lurbinectedin with or without avelumab in small cell carcinoma of the bladder (laser)-design and rationale.Future oncology (London, England) · 2025Article
- Clinical features and prognosis of small cell carcinoma of the bladder: a single center retrospective analysis.Translational andrology and urology · 2025Article
- Pathologic collision of urinary bladder urothelial carcinoma with small cell carcinoma: a case report.Diagnostic pathology · 2023Article
- The Application Effect of Traditional Chinese Medicine Nursing on General Anesthesia Combined with Epidural Anesthesia and Electric Resection for the Treatment of Bladder Cancer and Its Influence on Tumor Markers.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Successful treatment of recurrent small cell carcinoma of urinary bladder with pembrolizumab.IJU case reports · 2020Article
- A Case of Bladder Large Cell Carcinoma with Review of the Literature.Case reports in oncologyArticle
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionSmall cell carcinoma of urinary bladder is rare and has an aggressive malignant behavior and poor prognosis. Advanced bladder cancers are treated with immune checkpoint inhibitors, however, its efficacy for small cell carcinoma of urinary bladder is unclear. CASE PRESENTATION: A 54-year-old female, diagnosed with clinical stage T2N0M0 small cell carcinoma of urinary bladder, underwent radical cystectomy after three cycles of etoposide-cisplatin neoadjuvant chemotherapy. Despite the fact that pathological examination revealed no residual carcinoma in bladder in her cystectomy specimen, local recurrence of a 60-mm mass detected in the follow-up investigation 7.5 months later. This was completely treated by pembrolizumab without any adverse effects. Immunohistochemical staining revealed that the tumor had no programmed death ligand 1 expression but it showed CD8-positive T-lymphocyte infiltration into the tumor.
conclusionImmune checkpoint inhibitors might have curative potentials for treatment of small cell carcinoma of urinary bladder.
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