Evidence map›Paper›PMID 33163754›Full record

ArticleIEEE transactions on radiation and plasma medical sciences2020

Effects of TOF Resolution Models on Edge Artifacts in PET Reconstruction from Limited-Angle Data.

Paul Gravel, Yusheng Li, Samuel Matej

Abstract read
In one paragraph

Article in IEEE transactions on radiation and plasma medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Impact of detector parameters and image resolution modeling on dedicated brain PET imaging.IEEE transactions on radiation and plasma medical sciences · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. 2D feasibility study of joint reconstruction of attenuation and activity in limited angle TOF-PET.IEEE transactions on radiation and plasma medical sciences · 2021
    Article
  10. Article
  11. One-View Time-of-Flight Positron Emission Tomography Reconstruction.IEEE transactions on radiation and plasma medical sciences · 2021
    Article
  12. TOF-PET Image Reconstruction With Multiple Timing Kernels Applied on Cherenkov Radiation in BGO.IEEE transactions on radiation and plasma medical sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Paul GravelDepartment of Radiology, University of Pennsylvania, Philadelphia, PA.
Yusheng LiDepartment of Radiology, University of Pennsylvania, Philadelphia, PA.
Samuel MatejDepartment of Radiology, University of Pennsylvania, Philadelphia, PA.

Funding

Time-of-Flight PET for Improved Whole-Body ImagingR01CA113941 · NCI · UNIVERSITY OF PENNSYLVANIA · PI JOEL S KARP, Suleman Surti · 2006 to 2026
$9.8M
High Performance, Quantitative Breast PET Scanner Integrated With TomosynthesisR01CA196528 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ANDREW DOUGLAS ARNOLD MAIDMENT, Suleman Surti · 2016 to 2026
$5.9M
Development and application of 4D TOF reconstruction for quantitative PET imagingR01EB023274 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI MATEJ, SAMUEL · 2017 to 2020
$2.2M
NCI NIH HHS R01 CA113941NCI NIH HHS R01 CA196528NIBIB NIH HHS R01 EB023274
6 · The paper itself

Abstract

Limited-angle data, such as data obtained from a dual-panel Breast-PET scanner, result in substantial image blur in directions coinciding with the missing cone of the image spectrum. On systems with time-of-flight (TOF) capabilities, this blur is reduced as given by the TOF uncertainty, with the image spectrum being correspondingly expanded into the missing spectral cone. Modeling of the TOF uncertainty in the reconstruction is expected to deconvolve this residual TOF blurring. We have however observed that, as a tradeoff, this TOF de-blurring process also introduces ringing artifacts at the edges, analogous to the edge effects observed with line-of-response (LOR) resolution modeling, which attempts to deconvolve the blur due to detector resolution effects. However, in the former case, the ringing artifacts are much wider due to the spatial extent of the TOF uncertainty as compared to the width of typical LOR resolution blur. We illustrate and investigate the effects of using matched, as well as under-modeled and over-modeled, TOF kernels on edge artifacts in reconstruction from limited-angle data, and compare them with TOF reconstructions of complete data. Although for the conventional data with full angular coverage the reconstruction is fairly insensitive to the exact size of the TOF kernel and TOF modeling does not produce ringing artifacts, it is not the case for the limited-angle data. We show that it is important to use some form of regularization of the TOF uncertainty deconvolution process within reconstruction of the limited-angle data, such as decreasing the TOF kernel size.

Indexed as

Gibbs-like artifactslimited-angle data reconstructionPositron emission tomographytime-of-flight

Identifiers

PMID33163754
PMCPMC7643853

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