Evidence map›Paper›PMID 33163636›Full record

ArticleParasite epidemiology and control2020

Efficacy of Artemether-Lumefantrine on various

Enoch Aninagyei, Comfort Dede Tetteh, Martin Oppong, Alex Boye, Desmond Omane Acheampong

Open access · goldAbstract read
In one paragraph

Article in Parasite epidemiology and control, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Enoch AninagyeiUniversity of Health and Allied Sciences, School of Basic and Biomedical Sciences, Department of Biomedical Sciences, PMB 31, Ho-Volta Region, Ghana.
Comfort Dede TettehGhana Health Service, Municipal Health Directorate, Ga West Municipal, Amasaman, Ghana.
Martin OppongGhana Health Service, Municipal Health Directorate, Ga West Municipal, Amasaman, Ghana.
Alex BoyeUniversity of Cape Coast, School of Allied Health Sciences, Department of Medical Laboratory Science, Cape Coast, Ghana.
Desmond Omane AcheampongUniversity of Cape Coast, School of Allied Health Sciences, Department of Biomedical Sciences, Cape Coast, Ghana.
Ghana Health Service · GHUniversity of Cape Coast · GHUniversity of Health and Allied Sciences · GH

Funding

Wellcome Trust
6 · The paper itself

Abstract

introductionArtemether-Lumefantrine (A-L) remains the drug of choice for the treatment of uncomplicated malaria in Ghana. However, the pharmaco-activity of A-L has not been assessed on various

methodsThe clinical study was done in Ga West Municipality, Ghana, where 78 uncomplicated malaria patients were recruited with prior consent. The patients were treated orally with A-L according to national treatment guidelines. Baseline parasitaemia was determined before treatment and 8-hourly parasitaemia posttreatment were determined till initial clearance of parasitaemia and at days 7, 14, 21, and 28.

resultsFive

conclusionThis study reports the effectiveness of A-L on various

Indexed as

A, alanineACT, Artemisinin-based Combination TherapyA-L, Artemether-LumefantrineAmino acids:, A-alanineArtemether-LumefantrineAS-AQ, Artesunate-AmodiaquineC, cysteineCRC, clearance rate constantD, aspartic acidDHAP, Dihydroartemisinin-PiperaquinedsDNA, double stranded DNAF, phenylalanineG-6-PD, Glucose-6-phosphate dehydrogenaseGa West MunicipalG, glycineGhanaGHS, Ghana Health ServiceI, isoleucineKelch 13 gene mutationsN, asparagineParasite clearance characteristicsPCTs, parasite clearance timesPfmdr1 genesPfmdr1, Plasmodium multidrug resistance geneSNPs, Single nucleotide polymorphismssWGA, selective whole genome amplificationV, valineWHO, World Health OrganizationY, tyrosine

Identifiers

PMID33163636
PMCPMC7607505
OpenAlexW3094742892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.