ArticleMovement disorders clinical practice2020
Clinical Correlates of Functional Motor Disorders: An Italian Multicenter Study.
Article in Movement disorders clinical practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 54 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of Telemedicine on Health Outcomes (Clinical, Humanistic, Economic) in the Management of Patients With Functional Motor Disorder: Randomised Controlled Clinical Trial
Implementing a Digital Telerehabilitation Protocol and Non-motor Outcomes, and Quality of Life in Patients With Functional Motor Disorders: a Feasibility 2-arm Parallel Randomized Controlled Clinical Trial
A Window Into the Mind-brain-body Interplay: Development of Diagnostic, Prognostic Biomarkers and Rehabilitation Strategies in Functional Motor Disorders
Who cites it
54 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.
- Pain and functional neurological disorder: a systematic review and meta-analysis.Journal of neurology, neurosurgery, and psychiatry · 2024Pooled it
- Clinical outcomes and economic impact of a digital telemedicine intervention in patients with functional motor disorders: a single-blind, randomised controlled trial.Journal of neurology, neurosurgery, and psychiatry · 2025Trial
- Epidemiology and clinical features of movement disorders in a Mexican Mestizo cohort: a 10-year tertiary-center study.Arquivos de neuro-psiquiatria · 2026Article
- Multimodal assessment of clinical and neural changes following multidisciplinary management in functional motor disorders.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Aetiological factors in functional seizures and functional motor symptoms: shared and distinct features.Journal of neurology, neurosurgery, and psychiatry · 2026Article
- Challenges in the diagnosis and management of functional movement disorders in a developing nation: insights from the Philippines.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Functional Connectivity Gradients Reveal Altered Hierarchical Cortical Organization in Functional Neurological Disorder.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Pain in Functional Motor Disorders: Clinical Correlates From the Italian Registry.European journal of neurology · 2026Article
- Identifying diagnostic biomarkers in functional motor disorders through multimodal behavioral, neurophysiological, and imaging assessment using explainable machine learning.Journal of neurology · 2026Observational
- Exploring the Dynamic Relationship Between Migraine and Functional Neurological Disorders: A Narrative Review.Current pain and headache reports · 2026Review
- Clinical features of adolescent-onset functional motor disorders in tertiary movement disorders centers.Journal of neurology · 2026Observational
- Polyelectromyography Under Propofol to Differentiate Functional from Idiopathic Dystonia: A Pilot Study.Movement disorders : official journal of the Movement Disorder Society · 2026Article
- Functional Connectivity Predictors and Mechanisms of Symptom Change in Functional Neurological Disorder.medRxiv : the preprint server for health sciences · 2026Article
- Functional connectivity predictors and mechanisms of symptom change in functional neurological disorder.Brain communications · 2026Article
- Relationships between brain functional connectivity and resting cardiac autonomic profiles in functional neurological disorder: A pilot study.NeuroImage. Clinical · 2026Article
- The Complex Pathway of Conventional Investigations before the Diagnosis of Functional Motor Disorders.Movement disorders clinical practice · 2025Article
- Functional/dissociative seizures: Proposal for a new diagnostic label and definition by the ILAE task force.Epilepsia · 2025Article
- A case series of functional movement disorders in paediatric population-phenomenology and clinical characteristics.Acta neurologica Belgica · 2025Article
- Characterising alexithymia in individuals with functional motor disorders: a cross-sectional analysis of the Italian Registry of Functional Motor Disorders.Journal of neurology, neurosurgery, and psychiatry · 2025Article
- Functional Movement Disorder: Evolving Mechanisms, Diagnostic Precision, and Personalized Multidisciplinary Care.Movement disorders clinical practice · 2025Review
Corrections and comments
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Authors and funding
36 authors at 20 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFunctional motor disorders (FMDs) are abnormal movements that are significantly altered by distractive maneuvers and are incongruent with movement disorders seen in typical neurological diseases.
objectiveThe objectives of this article are to (1) describe the clinical manifestations of FMDs, including nonmotor symptoms and occurrence of other functional neurological disorders (FND); and (2) to report the frequency of isolated and combined FMDs and their relationship with demographic and clinical variables.
methodsFor this multicenter, observational study, we enrolled consecutive outpatients with a definite diagnosis of FMDs attending 25 tertiary movement disorders centers in Italy. Each patient underwent a detailed clinical evaluation with a definition of the phenotype and number of FMDs (isolated, combined) and an assessment of associated neurological and psychiatric symptoms.
resultsOf 410 FMDs (71% females; mean age, 47 ± 16.1 years) the most common phenotypes were weakness and tremor. People with FMDs had higher educational levels than the general population and frequent nonmotor symptoms, especially anxiety, fatigue, and pain. Almost half of the patients with FMDs had other FNDs, such as sensory symptoms, nonepileptic seizures, and visual symptoms. Patients with combined FMDs showed a higher burden of nonmotor symptoms and more frequent FNDs. Multivariate regression analysis showed that a diagnosis of combined FMDs was more likely to be delivered by a movement disorders neurologist. Also, FMD duration, pain, insomnia, diagnosis of somatoform disease, and treatment with antipsychotics were all significantly associated with combined FMDs.
conclusionsOur findings highlight the need for multidimensional assessments in patients with FMDs given the high frequency of nonmotor symptoms and other FNDs, especially in patients with combined FMDs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.