Evidence map›Paper›PMID 33163555›Full record

ArticleJournal of patient-centered research and reviews2020

Cole Relaxation Frequency as a Prognostic Parameter for Breast Cancer.

William D Gregory, Shahila Mehboob Christie, John Shell, Georges J Nahhas, Maharaj Singh, Wendy Mikkelson

Abstract read
In one paragraph

Article in Journal of patient-centered research and reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Action Items for Breast Cancer Awareness Month.Journal of patient-centered research and reviews · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

William D GregoryNovaScan, Inc., Milwaukee, WI.
Shahila Mehboob ChristieNovaScan, Inc., Milwaukee, WI.
John ShellNovaScan, Inc., Milwaukee, WI.
Georges J NahhasDepartment of Psychiatry & Behavioral Sciences and Hollings Cancer Center Biostatistics Shared Resource, Medical University of South Carolina, Charleston, SC.
Maharaj SinghBiostatistics, Marquette University School of Dentistry, Milwaukee, WI.
Wendy MikkelsonAurora Comprehensive Breast Health Center, Aurora St. Luke's Medical Center, Milwaukee, WI.

Funding

Translational Science Laboratory Shared ResourceP30CA138313 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI RAYMOND N. DUBOIS · 2009 to 2026
$42.7M
NCI NIH HHS P30 CA138313
6 · The paper itself

Abstract

We previously reported successful classification of breast cancer versus benign tissue using the Cole relaxation frequency measured on tissue excised during breast surgery as part of a study at two urban hospitals in the U.S. Midwest. Using that health system's cancer registry, we have discovered retrospectively that outcomes for patients who participated in the initial study can be classified correctly in 3 well-differentiated categories: nonrecurrent (NR); recurrent with no metastasis (RNM); and recurrent with metastasis (RM). As Cole relaxation frequency increases, the classification moves from NR to RNM and finally to RM. Multivariate analysis showed a significant association of "time-cancer-free" for all patients in these recurrent categories, with P-values ranging between 0.0001 to 0.0047. Thus, this follow-up report shows the potential feasibility of using Cole relaxation frequency as a prognostic parameter in a larger prospective study.

Indexed as

bioelectrical impedancebreast cancerCole relaxation frequencyprognosisrecurrence

Identifiers

PMID33163555
PMCPMC7644131

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.