Evidence map›Paper›PMID 33163463›Full record

ArticleFrontiers in pediatrics2020

Randomized Control Trial of Postnatal rhIGF-1/rhIGFBP-3 Replacement in Preterm Infants:

Sandra Horsch, Alessandro Parodi, Boubou Hallberg, Mariya Malova, Isabella M Björkman-Burtscher, Ingrid Hansen-Pupp, Neil Marlow, Kathryn Beardsall, David Dunger, Mirjam van Weissenbruch and 8 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Hemangioma-related gene polymorphisms in the pathogenesis of intraventricular hemorrhage in preterm infants.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023
    Article
  8. Article
  9. Article
  10. Neurovascular abnormalities in retinopathy of prematurity and emerging therapies.Journal of molecular medicine (Berlin, Germany) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 13 institutions in 7 countries.

Sandra HorschHELIOS Klinikum Berlin-Buch, Berlin, Germany.
Alessandro ParodiNeonatal Intensive Care Unit, Department Mother and Child, IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Istituto Giannina Gaslini, Genoa, Italy.
Boubou HallbergDepartment of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
Mariya MalovaNeonatal Intensive Care Unit, Department Mother and Child, IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Istituto Giannina Gaslini, Genoa, Italy.
Isabella M Björkman-BurtscherDepartment of Clinical Sciences Lund, Radiology, Skåne University Hospital, Lund University, Lund, Sweden.
Ingrid Hansen-PuppDepartment of Clinical Sciences Lund, Pediatrics, Skåne University Hospital, Lund University, Lund, Sweden.
Neil MarlowDepartment of Academic Neonatology, UCL Elizabeth Garrett Anderson Institute for Women's Health, University College London, London, United Kingdom.
Kathryn BeardsallDepartment of Paediatrics, University of Cambridge, Cambridge, United Kingdom.
David DungerDepartment of Paediatrics, University of Cambridge, Cambridge, United Kingdom.
Mirjam van WeissenbruchDepartment of Pediatrics, Division of Neonatology, Vrije Universiteit University Medical Center, Amsterdam UMC, Amsterdam, Netherlands.
Lois E H SmithHarvard Medical School, Boston Children's Hospital, Boston, MA, United States.
Mohamed HamdaniGlobal Clinical Development, Rare Metabolic Diseases, Shire, a Takeda Company, Lexington, MA, United States.
Alexandra MangiliGlobal Clinical Development, Rare Metabolic Diseases, Shire, a Takeda Company, Zurich, Switzerland.
Norman BartonGlobal Clinical Development, Rare Metabolic Diseases, Shire, a Takeda Company, Lexington, MA, United States.
Luca A RamenghiNeonatal Intensive Care Unit, Department Mother and Child, IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Istituto Giannina Gaslini, Genoa, Italy.
Ann HellströmInstitute of Neuroscience and Physiology, Sahlgrenska Academy, Gothenburg, Sweden.
David LeyDepartment of Clinical Sciences Lund, Pediatrics, Skåne University Hospital, Lund University, Lund, Sweden.
ROPP-2008-01 Study Team
Istituti di Ricovero e Cura a Carattere Scientifico · ITLund University · SETakeda (United States) · USUniversity of Cambridge · GBHarvard University · USHelios Hospital Berlin-Buch · DEIstituto Giannina Gaslini · ITKarolinska Institutet · SESkåne University Hospital · SETakeda (Switzerland) · CHUniversity College Hospital · GBUniversity of Gothenburg · SEVrije Universiteit Amsterdam · NL

Funding

Dietary control of angiogenesis in retinopathy modelsR01EY017017 · NEI · BOSTON CHILDREN'S HOSPITAL · PI Zhongjie Fu, Lois Smith · 2006 to 2026
$11.8M
Mouse Neurodevelopmental Behavior CoreU54HD090255 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI CHEN, CHINFEI · 2016 to 2020
$5.2M
Glucose/lipid metabolism and vessel development in phase I ROPR01EY030904 · NEI · BOSTON CHILDREN'S HOSPITAL · PI SMITH, LOIS · 2020 to 2023
$1.7M
PEDIATRIC EYE DISEASE INVESTIGATOR GROUP: CHAIR'S OFFICEU10EY023198 · NEI · INDIANA UNIVERSITY INDIANAPOLIS · PI WALLACE, DAVID K · 2014 to 2018
$1.4M
Department of Health 11/133/07NEI NIH HHS R01 EY017017NEI NIH HHS R01 EY030904NEI NIH HHS U10 EY023198NICHD NIH HHS U54 HD090255
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

brain injurycerebral hemorrhageextremely pretermneonaterecombinant human IGF-1

Identifiers

PMID33163463
PMCPMC7581737
OpenAlexW3092574191

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.