ArticleTzu chi medical journal
Significant association factors of bone mineral density in Taiwan adults.
Article in Tzu chi medical journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Association of Serum Phosphate, Calcium and Alkaline Phosphatase With Risk of Incident Fractures in Healthy Older Adults.The Journal of clinical endocrinology and metabolism · 2024Trial
- Association of serum alkaline phosphatase levels with bone mineral density, osteoporosis prevalence, and mortality in US adults with osteoporosis: evidence from NHANES 2005-2018.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Article
- The relationship between serum total alkaline phosphatase and risk of osteoporosis: a cross-sectional study.Frontiers in endocrinology · 2025Article
- A diagnostic approach integrated multimodal radiomics with machine learning models based on lumbar spine CT and X-ray for osteoporosis.Journal of bone and mineral metabolism · 2023Article
- Clinical Characteristics of Elderly People with Osteoporotic Vertebral Compression Fracture Based on a 12-Year Single-Center Experience in Korea.Geriatrics (Basel, Switzerland) · 2022Article
- The correlation between serum total alkaline phosphatase and bone mineral density in young adults.BMC musculoskeletal disorders · 2022Article
- Stimulant use and bone health in US children and adolescents: analysis of the NHANES data.European journal of pediatrics · 2022Article
- Alkaline phosphatase and acid phosphatase in health and disease - A systematic review.Journal of oral and maxillofacial pathology : JOMFPReview
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine the biofactors associated with bone mineral density (BMD) in southern Taiwanese adults. MATERIALS AND
methodsThe medical records of 3242 adults who underwent health examinations between June 2014 and February 2018 at a regional hospital in southern Taiwan were reviewed. The data collected included health history, anthropomorphic characteristics, clinical laboratory results, biochemical parameters, and BMD. The data were used to identify the biofactors associated with BMD/T-scores at the lumbar spine and femoral neck by multivariate linear regression analysis with the stepwise method.
resultsThe mean age of the patients was 58.1 years, and 71.4% were male. Factors positively correlated with BMD and the T-score included body mass index (BMI), male gender, calcium, and creatinine. Age, alkaline phosphatase (ALP), triiodothyronine, serum thyroxine, low-density lipoprotein cholesterol, and a history of hyperlipidemia were negatively correlated with BMD and the T-score.
conclusionThe associated biofactors reported here were similar to and had similar relationships as the biofactors identified in previous literature reports. Not all of the sites examined for BMD were influenced by the same association factors, except for BMI, male gender, age, and ALP, implying that the bone remodeling processes that shape BMD involve a complex regulatory network and demonstrating that our extracted factors are the most useful for clinical practice.
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