Evidence map›Paper›PMID 33163017›Full record

ArticleAfrican health sciences2020

Anti-retro viral therapy adverse drug reaction and associated factors among human immuno deficiency virus infected adult patients at Nigist Eleni Mohammed Memorial hospital, South Ethiopia.

Temesgen Tamirat, Kifle Woldemichael, Tsegaye Tewelde, Tariku Laelago

Open access · diamondAbstract read
In one paragraph

Article in African health sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Incidence and Predictors of Severe Adverse Drug Reactions among Patients on Antiretroviral Drugs in Harari Regional State, Eastern Ethiopia.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Temesgen TamiratWachemo university, Hosanna, Ethiopia.
Kifle WoldemichaelJimma university, Jimma, Ethiopia.
Tsegaye TeweldeJimma university, Jimma, Ethiopia.
Tariku LaelagoWachemo university Durame campus, Durame, Ethiopia.
Jimma University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent increases in access to HAART have made the management of drug toxicities an increasingly crucial component of HIV care in developing countries. The aim of this study was to determine prevalence of antiretroviral therapy adverse drug reactions and associated factors among HIV-infected adult patients at Nigist Eleni Mohammed memorial hospital.

methodsA cross sectional study was conducted by retrospective review of patients' medical records. From a total 721 adult patient records, 231 patients record were selected by simple random sampling technique. The study was conducted April 15-25, 2015.The association between dependent and independent variables was measured by using OR at 95% CI. P-value <0.05 was considered as statistically significant.

resultAbout 53(22.9%) patients developed ADRs (adverse drug reactions). Female (AOR=2.72, CI=1.177-6.30), patients with WHO stage III and IV (AOR= 13.06, CI=4.17-40.90) were found more likely to develop ADRs. Commonly identified ADRs were fatigue (18.1%), diarrhea (7.7%), nausea (6.5%), headache (3.6%) and anemia (2%).

conclusionNearly one in five patients develop ADRs. Sex of respondents, WHO stage and functional status were associated with ADRs. The health care providers should give due attention to ambulatory, bedridden, and WHO stage III and IV patients.

Indexed as

AdultAnti-Retroviral AgentsAntiretroviral Therapy, Highly ActiveCross-Sectional StudiesDrug-Related Side Effects and Adverse ReactionsEthiopiaFemaleHIV InfectionsHumansMaleMiddle AgedPrevalenceRetrospective StudiesRisk FactorsYoung AdultAnti-Retroviral AgentsAIDSARTEthiopiaHIV

Identifiers

PMID33163017
PMCPMC7609072
OpenAlexW3045288796

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.