Evidence map›Paper›PMID 33162897›Full record

ArticleFrontiers in physiology2020

A Novel Fibroblast Reporter Cell Line for

Julia Nemeth, Annika Schundner, Karsten Quast, Veronika E Winkelmann, Manfred Frick

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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  6. Review
  7. Adiponectin suppresses stiffness-dependent, profibrotic activation of lung fibroblasts.American journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  8. Article
  9. The evolution ofEuropean respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Julia NemethInstitute of General Physiology, Ulm University, Ulm, Germany.
Annika SchundnerInstitute of General Physiology, Ulm University, Ulm, Germany.
Karsten QuastBoehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany.
Veronika E WinkelmannInstitute of General Physiology, Ulm University, Ulm, Germany.
Manfred FrickInstitute of General Physiology, Ulm University, Ulm, Germany.
Universität Ulm · DEBoehringer Ingelheim (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Idiopathic pulmonary fibrosis (IPF) is a fatal disease of the lower respiratory tract with restricted therapeutic options. Repetitive injury of the bronchoalveolar epithelium leads to activation of pulmonary fibroblasts, differentiation into myofibroblasts and excessive extracellular matrix (ECM) deposition resulting in aberrant wound repair. However, detailed molecular and cellular mechanisms underlying initiation and progression of fibrotic changes are still elusive. Here, we report the generation of a representative fibroblast reporter cell line (10-4A

Indexed as

alpha smooth muscle actinextracellular matrixidiopathic pulmonary fibrosislungmyofibroblastTGF-β

Identifiers

PMID33162897
PMCPMC7582034
OpenAlexW3092051615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.