Evidence map›Paper›PMID 33162895›Full record

ArticleFrontiers in physiology2020

Circadian, Sleep and Caloric Intake Phenotyping in Type 2 Diabetes Patients With Rare Melatonin Receptor 2 Mutations and Controls: A Pilot Study.

Akram Imam, Eva C Winnebeck, Nina Buchholz, Philippe Froguel, Amélie Bonnefond, Michele Solimena, Anna Ivanova, Michel Bouvier, Bianca Plouffe, Guillaume Charpentier and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 5 countries.

Akram ImamDepartment of Integrative Physiology, University of Colorado Boulder, Boulder, CO, United States.
Eva C WinnebeckInstitute of Medical Psychology, Ludwig Maximilian University, Munich, Germany.
Nina BuchholzInstitute of Medical Psychology, Ludwig Maximilian University, Munich, Germany.
Philippe FroguelInserm UMR1283, CNRS UMR8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille University Hospital, Lille, France.
Amélie BonnefondInserm UMR1283, CNRS UMR8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille University Hospital, Lille, France.
Michele SolimenaPaul Langerhans Institute Dresden of the Helmholtz Center Munich at the Technische Universität Dresden, Dresden, Germany.
Anna IvanovaPaul Langerhans Institute Dresden of the Helmholtz Center Munich at the Technische Universität Dresden, Dresden, Germany.
Michel BouvierDepartment of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, QC, Canada.
Bianca PlouffeDepartment of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, QC, Canada.
Guillaume CharpentierCentre d'Études et de Recherches pour l'Intensification du Traitement du Diabète (CERITD), Sud-Francilien Hospital, Corbeil-Essonnes, France.
Angeliki KaramitriUniversité de Paris, Institut Cochin, INSERM, CNRS, Paris, France.
Ralf JockersUniversité de Paris, Institut Cochin, INSERM, CNRS, Paris, France.
Till RoennebergInstitute of Medical Psychology, Ludwig Maximilian University, Munich, Germany.
Céline VetterDepartment of Integrative Physiology, University of Colorado Boulder, Boulder, CO, United States.
Ludwig-Maximilians-Universität München · DEEuropean Genomic Institute for Diabetes · FRUniversité de Montréal · CAUniversity of Colorado Boulder · USCentre d'Etudes et de Recherches pour l'Intensification du Traitement du Diabète · FRCentre National de la Recherche Scientifique · FRPaul Langerhans Institute Dresden · DETU Dresden · DEUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMelatonin modulates circadian rhythms in physiology and sleep initiation. Genetic variants of the MATERIALS AND

methodsIn this pilot study, 28 individuals [50% male; 46-82 years old; 50% with rare MT

resultsPatients with rare MT

conclusionThis pilot study suggests that compared to diabetic controls, T2D MT

Indexed as

circadian misalignmentdiabetesdietMT2MTNR1Bsleepsocial jetlag

Identifiers

PMID33162895
PMCPMC7583701
OpenAlexW3092495569

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.