Evidence map›Paper›PMID 33162894›Full record

ArticleFrontiers in physiology2020

A Novel Computational Model of the Rabbit Atrial Cardiomyocyte With Spatial Calcium Dynamics.

Márcia R Vagos, Hermenegild Arevalo, Jordi Heijman, Ulrich Schotten, Joakim Sundnes

Abstract read
In one paragraph

Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Role of ryanodine receptor cooperativity in CaThe Journal of physiology · 2024
    Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Márcia R VagosSimula Research Laboratory, Computational Physiology Department, Lysaker, Norway.
Hermenegild ArevaloSimula Research Laboratory, Computational Physiology Department, Lysaker, Norway.
Jordi HeijmanFaculty of Health, Medicine and Life Sciences, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, Netherlands.
Ulrich SchottenFaculty of Health, Medicine and Life Sciences, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, Netherlands.
Joakim SundnesSimula Research Laboratory, Computational Physiology Department, Lysaker, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Models of cardiac electrophysiology are widely used to supplement experimental results and to provide insight into mechanisms of cardiac function and pathology. The rabbit has been a particularly important animal model for studying mechanisms of atrial pathophysiology and atrial fibrillation, which has motivated the development of models for the rabbit atrial cardiomyocyte electrophysiology. Previously developed models include detailed representations of membrane currents and intracellular ionic concentrations, but these so-called "common-pool" models lack a spatially distributed description of the calcium handling system, which reflects the detailed ultrastructure likely found in cells

Indexed as

calcium wavescomputational modelcorrelation analysispopulation of modelsrabbit atrial cardiomyocytespatial calcium dynamics

Identifiers

PMID33162894
PMCPMC7583320

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.