Evidence map›Paper›PMID 33162633›Full record

ArticleMaterials & design2021

Effects of systematically varied thiourethane-functionalized filler concentration on polymerization behavior and relevant clinical properties of dental composites.

S H Lewis, Fugolin App, S Lam, C Scanlon, J L Ferracane, C S Pfeifer

Abstract read
In one paragraph

Article in Materials & design, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Initiator-dependent effects of thiourethane on resin cement curing under light attenuation conditions.Dental materials : official publication of the Academy of Dental Materials · 2026
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

S H LewisOregon Health & Science University, Department of Restorative Dentistry, Biomaterials and Biomechanics, United States of America.
Fugolin AppOregon Health & Science University, Department of Restorative Dentistry, Biomaterials and Biomechanics, United States of America.
S LamApprenticeships in Science and Engineering (ASE, Saturday Academy), United States of America.
C ScanlonOregon Health & Science University, Department of Restorative Dentistry, Biomaterials and Biomechanics, United States of America.
J L FerracaneOregon Health & Science University, Department of Restorative Dentistry, Biomaterials and Biomechanics, United States of America.
C S PfeiferOregon Health & Science University, Department of Restorative Dentistry, Biomaterials and Biomechanics, United States of America.

Funding

Novel polymeric materials with improved durability in the oral environment: tailoring responses to host and bacterial enzymes with anti-proteolytic and ecology-based antimicrobial approaches.R35DE029083 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI Carmem S. Pfeifer · 2019 to 2026
$8.1M
Tertiary methacrylamides and thiourethane additives as novel dental compositesU01DE023756 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI FERRACANE, JACK L., PFEIFER, CARMEM S. · 2013 to 2017
$2.4M
Smart Self-Sterilizing Dental Composites for Class V RestorationsR01DE026113 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI FERRACANE, JACK L., MERRITT, JUSTIN · 2016 to 2018
$1.2M
Novel dental composites based on methacrylamides and thiourethane oligomersK02DE025280 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI PFEIFER, CARMEM S. · 2016 to 2020
$600k
NIDCR NIH HHS K02 DE025280NIDCR NIH HHS R01 DE026113NIDCR NIH HHS R35 DE029083NIDCR NIH HHS U01 DE023756
6 · The paper itself

Abstract

Introduction of thiourethane (TU) oligomer to resin-based dental restorative materials reduces stress and improves fracture toughness without compromising conversion. Localization of TU at the resin-filler interface via silanization procedures may lead to more substantial stress reduction and clinical property enhancements. The objective of this study was to evaluate composite properties as a function of TU-functionalized filler concentration. TU oligomers were synthesized using click-chemistry techniques and subsequently silanized to barium glass filler. Resin-based composites were formulated using varying ratios of TU-functionalized filler and conventional methacrylate-silanized barium filler. Material property testing included thermogravimetric analysis, real-time polymerization kinetics and depth of cure, polymerization stress, stress relaxation and fracture toughness. Clinical property testing included water sorption/solubility, composite paste viscosity, and gloss and surface roughness measured before and after subjecting the samples to 6 h of continuous tooth brushing in a custom-built apparatus using a toothpaste/water mixture. Increasing TU-filler in the composite resulted in as much as a 78% reduction in stress, coupled with an increase in fracture toughness. Conversion was similar for all groups. After simulated tooth brushing, gloss reduction was lower for TU-containing composites and surface roughness was less than or equal to the control.

Indexed as

Dental compositesDimethacrylatesFracture toughnessPolymerization stressSurface propertiesThiourethane oligomers

Identifiers

PMID33162633
PMCPMC7641517

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.