Evidence map›Paper›PMID 33162563›Full record

ArticleEuropean polymer journal2020

Tuning small molecule release from polymer micelles: Varying H

Ryan J Carrazzone, Jeffrey C Foster, Zhao Li, John B Matson

Open access · greenAbstract read
In one paragraph

Article in European polymer journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Amino acid-based HChemical communications (Cambridge, England) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ryan J CarrazzoneDepartment of Chemistry, Center for Drug Discovery, and Macromolecules Innovation Institute, Virginia Tech, Blacksburg, VA, 24061, United States.ORCID 0000-0003-4629-086X
Jeffrey C FosterDepartment of Chemistry, Center for Drug Discovery, and Macromolecules Innovation Institute, Virginia Tech, Blacksburg, VA, 24061, United States.ORCID 0000-0002-9097-8680
Zhao LiDepartment of Chemistry, Center for Drug Discovery, and Macromolecules Innovation Institute, Virginia Tech, Blacksburg, VA, 24061, United States.
John B MatsonDepartment of Chemistry, Center for Drug Discovery, and Macromolecules Innovation Institute, Virginia Tech, Blacksburg, VA, 24061, United States.ORCID 0000-0001-7984-5396
Virginia Tech · US

Funding

Delivery of H2S: Supramolecular and Enzyme-Triggered Strategies for Controlled ReleaseR01GM123508 · NIGMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI MATSON, JOHN B · 2017 to 2021
$1.6M
NIGMS NIH HHS R01 GM123508
6 · The paper itself

Abstract

Polymer micelles, used extensively as vehicles in the delivery of active pharmaceutical ingredients, represent a versatile polymer architecture in drug delivery systems. We hypothesized that degree of crosslinking in the hydrophobic core of amphiphilic block copolymer micelles could be used to tune the rate of release of the biological signaling gas (gasotransmitter) hydrogen sulfide (H

Identifiers

PMID33162563
PMCPMC7643851
OpenAlexW3089505205

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.