Evidence map›Paper›PMID 33162482›Full record

ArticleInternal medicine (Tokyo, Japan)2021

Two Cases of Autoimmune Neutropenia Complicated with Other Lineages of Autoimmune Cytopenia, Successfully Treated with Prednisolone.

Yoshiya Adachi, Yumi Yamazoe-Ishiguri, Satoshi Iwata, Atsushi Murase, Rika Kihara, Koichi Watamoto

Open access · diamondAbstract read
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yoshiya AdachiDepartment of Hematology, Komaki City Hospital, Japan.
Yumi Yamazoe-IshiguriDepartment of Hematology, Komaki City Hospital, Japan.
Satoshi IwataDepartment of Hematology, Komaki City Hospital, Japan.
Atsushi MuraseDepartment of Hematology, Komaki City Hospital, Japan.
Rika KiharaDepartment of Hematology, Komaki City Hospital, Japan.
Koichi WatamotoDepartment of Hematology, Komaki City Hospital, Japan.
Komaki City Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Though adult-onset primary autoimmune pancytopenia (AIP) rarely follows a self-limited course, a standard treatment strategy has not yet been established. We herein report two cases, each involving primary autoimmune neutropenia complicated with autoimmune thrombocytopenia or Evans syndrome. They were refractory to granulocyte-colony stimulating factor, but all lineages of cytopenia promptly recovered with prednisolone (PSL). In case 1, PSL was tapered and discontinued six months after its initiation without AIP relapse. In case 2, PSL has been tapered for five months without relapse. To establish an optimal treatment strategy for AIP, it is necessary to accumulate more cases.

Indexed as

Anemia, Hemolytic, AutoimmuneAutoimmune DiseasesNeutropeniaThrombocytopeniaAdultGranulocyte Colony-Stimulating FactorHumansPrednisoloneGranulocyte Colony-Stimulating FactorPrednisoloneantineutrophil antibodyautoimmune neutropeniaautoimmune pancytopeniaprednisolone

Identifiers

PMID33162482
PMCPMC8112969
OpenAlexW3101272483

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.