Evidence map›Paper›PMID 33161780›Full record

ArticleFoot & ankle international2021

Species-Specific Immunoassay Aids Identification of Pathogen and Tracks Infectivity in Foot Infection.

Stephanie P Hao, Elysia A Masters, Mark J Ninomiya, Christopher A Beck, Edward M Schwarz, John L Daiss, Irvin Oh

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Foot & ankle international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Transcriptomic identification of genes expressed in invasiveFrontiers in cellular and infection microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Stephanie P HaoCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, USA.ORCID https://orcid.org/0000-0002-3760-8234
Elysia A MastersCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, USA.
Mark J NinomiyaCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, USA.
Christopher A BeckDepartment of Biostatistics and Computational Biology, University of Rochester, Rochester, NY, USA.ORCID https://orcid.org/0000-0003-0672-0730
Edward M SchwarzCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, USA.
John L DaissCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, USA.
Irvin OhCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, USA.ORCID https://orcid.org/0000-0002-2648-5849
University of Rochester Medical Center · USUniversity of Rochester · US

Funding

Project 2: Defining the Protective vs. Susceptible Immune Proteome of S. aureus OsteomyelitisP50AR072000 · NIAMS · UNIVERSITY OF ROCHESTER · PI Edward M. Schwarz · 2017 to 2026
$13.6M
Rochester Resource-Based Center for Bone, Muscle and Orthopaedic Research (ROCSTARR) (Overall Application)P30AR069655 · NIAMS · UNIVERSITY OF ROCHESTER · PI Edward M. Schwarz · 2016 to 2026
$7.8M
Pathogen-specific and Prognosis of S. aureus infection in Orthopaedic SurgeryR21AR074571 · NIAMS · YALE UNIVERSITY · PI OH, IRVIN · 2018 to 2019
$376k
NIAMS NIH HHS P30 AR069655NIAMS NIH HHS P50 AR072000NIAMS NIH HHS R21 AR074571
6 · The paper itself

Abstract

backgroundConventional bacterial cultures frequently fail to identify the dominant pathogen in polymicrobial foot infections, in which

methodsFrom July 2015 to July 2019, 83 infected foot ulcer patients undergoing surgical intervention (debridement or amputation) were recruited and blood was drawn at 0, 4, 8, and 12 weeks. Whole blood was analyzed for

resultsAnalysis of serum for anti-

conclusionIn the management of foot infection, the use of LEVEL OF EVIDENCE: Level II, prospective comparative study.

Indexed as

Amputation, SurgicalBacterial InfectionsDiabetic FootFootHumansImmunoassayProspective StudiesStaphylococcal InfectionsStaphylococcus aureusantibody-secreting celldiabetic foot ulcerimmunoassaynewly synthesized antibodyS. aureus

Identifiers

PMID33161780
PMCPMC7946706
OpenAlexW3098659435

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.