ArticleHypertension (Dallas, Tex. : 1979)2021
Orthostatic Hypertension and Intensive Blood Pressure Control; Post-Hoc Analyses of SPRINT.
Article in Hypertension (Dallas, Tex. : 1979), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Effects of intensive blood pressure treatment on orthostatic hypertension: individual level meta-analysis.BMJ (Clinical research ed.) · 2025Pooled it
- Association of orthostatic hypertension identified according to different definitions with cardiovascular disease. The PARTAGE study.Journal of hypertension · 2026Article
- Hyperdynamic circulation distinguishes predominantly diastolic hypertension from predominantly systolic hypertension.Journal of human hypertension · 2025Article
- Hypertension and orthostatic hypertension in 85-year-olds and associations with mortality and cognitive decline in a longitudinal cohort study.Scientific reports · 2025Article
- Orthostatic and Standing Hypertension and Risk of Cardiovascular Disease.Hypertension (Dallas, Tex. : 1979) · 2025Article
- Differences in heart rate responses to upright posture are associated with variations in the high-frequency power of heart rate variability.American journal of physiology. Heart and circulatory physiology · 2024Article
- Orthostatic Hypertension: A Newcomer Among the Hypertension Phenotypes.Hypertension (Dallas, Tex. : 1979) · 2023Review
- Association between orthostatic blood pressure dysregulation and geriatric syndromes: a cross-sectional study.BMC geriatrics · 2022Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
We evaluated the association between orthostatic hypertension and cardiovascular outcomes and the effect of intensive blood pressure (BP) control on cardiovascular outcomes in patients with orthostatic hypertension. Post hoc analyses of the SPRINT (Systolic Blood Pressure Intervention Trial) data were conducted; orthostatic hypertension was defined as increase in systolic BP≥20 mm Hg or increase in diastolic BP≥10 mm Hg with standing. Of 9329 participants, 1986 (21.2%) had orthostatic hypertension at baseline. Within the intensive treatment group, participants with orthostatic hypertension were at higher risk of developing the composite cardiovascular outcome (hazard ratio, 1.44 [95% CI, 1.1-1.87],
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.