ArticleChild maltreatment2022
Childhood Abuse and Cognitive Function in a Large Cohort of Middle-Aged Women.
Article in Child maltreatment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Childhood maltreatment and cognitive functioning from young adulthood to late midlife: A prospective study.Neuropsychology · 2026Article
- Early-Life Parental Affection, Social Relationships in Adulthood, and Later-Life Cognitive Function.Journal of aging and health · 2026Article
- Childhood maltreatment confers long-term risk for cognitive impairment: A prospective investigation.The journal of prevention of Alzheimer's disease · 2025Article
- Article
- Intimate partner violence and cognitive functioning - toward quantifying dementia risk.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Early-Life Adversity Predicts Markers of Aging-Related Neuroinflammation, Neurodegeneration, and Cognitive Impairment in Women.Annals of neurology · 2025Article
- Childhood Sexual Trauma, Substance Use, and Antiretroviral Therapy Adherence Among Older Adults Living With HIV: A Mediational Analysis.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2025Article
- Sex Differences in the Associations Among Early Life Adversity, Inflammation, and Cognition.Biomolecules · 2025Review
- Post-traumatic stress disorder symptom remission and cognition in a large cohort of civilian women.Psychological medicine · 2024Article
- Maintenance of brain health: The role of social determinants of health and other non-traditional cardiovascular risks.Cerebral circulation - cognition and behavior · 2024Article
- Longitudinal association of adverse childhood experiences with cognitive function trajectories among middle-aged and older adults: group-based trajectory modeling.Frontiers in psychiatry · 2024Article
- Epigenetic age acceleration as a biomarker for impaired cognitive abilities in adulthood following early life adversity and psychiatric disorders.Neurobiology of stress · 2023Article
- Association of childhood trauma with cognitive domains in adult patients with mental disorders and in non-clinical populations: a systematic review.Frontiers in psychology · 2023Review
- Childhood Stressors, Relationship Quality, and Cognitive Health in Later Life.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022Article
- Residential Green Space and Cognitive Function in a Large Cohort of Middle-Aged Women.JAMA network open · 2022Article
- Association of Adverse Childhood Experiences With Poor Neuropsychiatric Health and Dementia Among Former Professional US Football Players.JAMA network open · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Cognitive function at middle age is of particular public health interest, as it strongly predicts later dementia. Children who have experienced abuse subsequently have worse cognitive function than those who have not. However, it remains unclear whether the association of abuse with cognitive function persists into middle age. In 2014-2016, 14,151 women ages 49-69 years who had previously responded to a childhood abuse questionnaire completed a cognitive battery. In models adjusted for childhood socioeconomic status and head trauma, combined physical, emotional, and sexual abuse was associated with lower scores on both Learning/Working Memory (severe abuse, lower scores similar to that observed in women 4.8 years older in our data) and Psychomotor Speed/Attention (severe abuse, lower scores similar to that observed in women to 2.9 years older in our data). Adjustment for adulthood socioeconomic status and health factors (e.g., smoking, hypertension) slightly attenuated associations. In exploratory analyses further adjusted for psychological distress, associations were attenuated. Women exposed versus unexposed to childhood abuse had poorer cognitive function at mid-life. Associations were particularly strong for learning and working memory and were not accounted for by adulthood health factors. Childhood abuse should be investigated as a potential risk factor for cognitive decline and dementia in old age.
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Registered trials
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