Evidence map›Paper›PMID 33161452›Full record

ArticleInternational journal of clinical oncology2021

Optimizing antiemetic treatment for chemotherapy-induced nausea and vomiting in Japan: Update summary of the 2015  Japan Society of Clinical Oncology Clinical Practice Guidelines for Antiemesis.

Kenjiro Aogi, Hideki Takeuchi, Toshiaki Saeki, Keisuke Aiba, Kazuo Tamura, Keiko Iino, Chiyo K Imamura, Kenji Okita, Yoshikazu Kagami, Ryuhei Tanaka and 17 more

Open access · hybridAbstract read
In one paragraph

Article in International journal of clinical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 7 pooled it
13.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 7 syntheses or guidelines pooled it, 107 citations in OpenAlex.

  1. Pooled it
  2. Clinical benefits of adding olanzapine to 5-HTInternational journal of clinical oncology · 2025
    Pooled it
  3. Pooled it
  4. Guideline
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  6. Palonosetron for prevention of delayed chemotherapy-induced nausea and vomiting in pediatric patients: a meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
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  8. Low dose of dexamethasone combined with netupitant and palonosetron in preventing nausea and vomiting in breast cancer patients induced by anthracycline drugs.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
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  16. Potentially preventable unplanned hospitalizations due to adverse events in patients receiving systemic anticancer therapy: a retrospective single-center study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  17. Article
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  20. Observational

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 19 institutions in 1 country.

Kenjiro AogiDepartment of Breast Oncology, National Hospital Organization Shikoku Cancer Center, Ehime, Japan.
Hideki TakeuchiDepartment of Breast Oncology, Saitama Medical University, Saitama, Japan.
Toshiaki SaekiDepartment of Breast Oncology, Saitama Medical University International Medical Center, Saitama, Japan. tsaeki@saitama-med.ac.jp.ORCID http://orcid.org/0000-0002-8893-9519
Keisuke AibaDivision of Clinical Oncology/Hematology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan.
Kazuo TamuraGeneral Medical Research Center, Fukuoka University Hospital, Fukuoka, Japan.
Keiko IinoDepartment of Adult Nursing, National College of Nursing, Tokyo, Japan.
Chiyo K ImamuraDepartment of Clinical Pharmacokinetics and Pharmacodynamics, Keio University, Tokyo, Japan.
Kenji OkitaDepartment of Surgery, Surgical Oncology and Science, Sapporo Medical University Postgraduate School of Medicine, Sapporo, Hokkaido, Japan.
Yoshikazu KagamiDivision of Radiation Oncology, Department of Radiology, Showa University School of Medicine, Tokyo, Japan.
Ryuhei TanakaDepartment of Pediatric Hematology and Oncology, Saitama Medical University International Medical Center, Saitama, Japan.
Kazuhiko NakagawaDepartment of Medical Oncology, Faculty of Medicine, Kindai University, Osaka, Japan.
Hirofumi FujiiDepartment of Clinical Oncology, Jichi Medical University, Tochigi, Japan.
Narikazu BokuGastrointestinal Medical Oncology Division, National Cancer Center Hospital, Tokyo, Japan.
Makoto WadaDepartment of Psycho-Oncology and Palliative Medicine, Osaka International Cancer Institute, Osaka, Japan.
Tatsuo AkechiDepartment of Psychiatry and Cognitive-Behavioral Medicine, Nagoya City University Graduate School of Medical Sciences, Aichi, Japan.
Hirotoshi IiharaDepartment of Pharmacy, Gifu University Hospital, Gifu, Japan.
Shoichiro OhtaniDepartment of Breast Surgery, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.
Ayako OkuyamaCenter for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan.
Keiko OzawaDepartment of Nursing, NTT Medical Center Tokyo, Tokyo, Japan.
Yong-Il KimDepartment of Medical Oncology, Seirei Hamamatsu General Hospital, Sizuoka, Japan.
Hidenori SasakiDivision of Medical Oncology, Hematology and Infectious Disease, Department of Medicine, Fukuoka University Hospital, Fukuoka, Japan.
Yasuo ShimaDepartment of Palliative Medicine, Tsukuba Medical Center Hospital, Ibaraki, Japan.
Masayuki TakedaDepartment of Medical Oncology, Faculty of Medicine, Kindai University, Osaka, Japan.
Eijiro NagasakiDivision of Clinical Oncology/Hematology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan.
Toshihiko NishidateDepartment of Surgery, Surgical Oncology and Science, Sapporo Medical University Postgraduate School of Medicine, Sapporo, Hokkaido, Japan.
Takahiro HigashiCenter for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan.
Kouichi HirataDepartment of Surgery, Surgical Oncology and Science, Sapporo Medical University Postgraduate School of Medicine, Sapporo, Hokkaido, Japan.
Sapporo Medical University · JPFukuoka University Hospital · JPJikei University School of Medicine · JPKindai University · JPShowa University · JPGifu University Hospital · JPHiroshima City Asa Citizens Hospital · JPJichi Medical University · JPNagoya City University · JPNational Cancer Center Hospital East · JPNational College Of Nursing · JPNTT Medical Center · JPOsaka International Cancer Institute · JPSaitama International Medical Center · JPSaitama Medical University · JPShikoku Cancer Center · JPTsukuba Medical Center Hospital · JPYodogawa Christian Hospital · JPYokohama Rosai Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with cancer should appropriately receive antiemetic therapies against chemotherapy-induced nausea and vomiting (CINV). Antiemetic guidelines play an important role in managing CINV. Accordingly, the first Japanese antiemetic guideline published in 2010 by the Japan Society of Clinical Oncology (JSCO) has considerably aided Japanese medical staff in providing antiemetic therapies across chemotherapy clinics. With the yearly advancements in antiemetic therapies, the Japanese antiemetic guidelines require revisions according to published evidence regarding antiemetic management worldwide. A revised version of the first antiemetic guideline that considered several upcoming evidences had been published online in 2014 (version 1.2), in which several updated descriptions were included. The 2015 JSCO clinical practice guideline for antiemesis (version 2.0) (in Japanese) has addressed clinical antiemetic concerns and includes four major revisions regarding (1) changes in emetogenic risk categorization for anti-cancer agents, (2) olanzapine usage as an antiemetic drug, (3) the steroid-sparing method, and (4) adverse drug reactions of antiemetic agents. We herein present an English update summary for the 2015 JSCO clinical practice guideline for antiemesis (version 2.0).

Indexed as

AntiemeticsAntineoplastic AgentsNeoplasmsHumansJapanMedical OncologyNauseaVomitingAntiemeticsAntineoplastic AgentsAntiemesisChemotherapy-induced nausea and vomitingClinical practice guideline

Identifiers

PMID33161452
PMCPMC7788035
OpenAlexW3098618379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.