SynthesisDiabetes & metabolic syndrome
Charlson comorbidity index and a composite of poor outcomes in COVID-19 patients: A systematic review and meta-analysis.
Synthesis in Diabetes & metabolic syndrome. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 184 papers, 10 of them syntheses that pooled it.
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Who cites it
184 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- Endotheliopathy marked by high von Willebrand factor (vWF) antigen in COVID-19 is associated with poor outcome: a systematic review and meta-analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022Pooled it
- Dipeptidyl peptidase-4 (DPP-IV) inhibitor was associated with mortality reduction in COVID-19 - A systematic review and meta-analysis.Primary care diabetes · 2022Pooled it
- Effect of colchicine on mortality in patients with COVID-19 - A systematic review and meta-analysis.Diabetes & metabolic syndrome · 2022Pooled it
- Fibrosis-4 index and mortality in coronavirus disease 2019: a meta-analysis.European journal of gastroenterology & hepatology · 2021Pooled it
- Active prescription of low-dose aspirin during or prior to hospitalization and mortality in COVID-19: A systematic review and meta-analysis of adjusted effect estimates.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021Pooled it
- Colchicine and mortality in patients with coronavirus disease 2019 (COVID-19) pneumonia: A systematic review, meta-analysis, and meta-regression.International immunopharmacology · 2021Pooled it
- Visceral adiposity, subcutaneous adiposity, and severe coronavirus disease-2019 (COVID-19): Systematic review and meta-analysis.Clinical nutrition ESPEN · 2021Pooled it
- The Prognostic Value of Hyponatremia for Predicting Poor Outcome in Patients With COVID-19: A Systematic Review and Meta-Analysis.Frontiers in medicine · 2021Pooled it
- Hypocalcemia is associated with severe COVID-19: A systematic review and meta-analysis.Diabetes & metabolic syndromePooled it
- Delirium and Mortality in Coronavirus Disease 2019 (COVID-19) - A Systematic Review and Meta-analysis.Archives of gerontology and geriatricsPooled it
- The impact of a disparity-reduction intervention on outcomes of patients with acute coronary syndrome in the emergency department: a clinical trial.International journal for equity in health · 2025Trial
- Association of laboratory and radiological findings during hospitalization with early post-COVID pulmonary function and exercise capacity: a retrospective study.BMC pulmonary medicine · 2026Article
- Comparison of chest X-ray radiography AI model to comorbidities for predicting intensive care unit admission for COVID-19.Journal of medical imaging (Bellingham, Wash.) · 2026Article
- Serum Renin: An Early Biomarker for Predicting Severe Acute Pancreatitis.Digestive diseases and sciences · 2026Article
- Association between prolonged Emergency Department stay and Intensive Care Unit mortality among patients at a tertiary hospital in Ethiopia.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2026Article
- Predicting Falls With the Morse Fall Scale: A Retrospective Assessment at the Veterans Health Administration.Clinical nursing research · 2026Article
- Post-COVID-19 physical and mental quality of life: a latent profile analysis and predictive factors.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Prognostic Value of Charlson Comorbidity Index in Patients with COVID-19.Tropical medicine and infectious disease · 2026Article
- Prescribing Practices, Polypharmacy, and Drug Interaction Risks in Anticoagulant Therapy: Insights from a Secondary Care Hospital.Journal of clinical medicine · 2026Article
- Lactate to albumin ratio predicts one year mortality in ICU patients receiving invasive mechanical ventilation.Scientific reports · 2026Article
124 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsThe ongoing COVID-19 pandemic is disproportionately affecting patients with comorbidities. Therefore, thorough comorbidities assessment can help establish risk stratification of patients with COVID-19, upon hospital admission. Charlson Comorbidity Index (CCI) is a validated, simple, and readily applicable method of estimating the risk of death from comorbid disease and has been widely used as a predictor of long-term prognosis and survival.
methodsWe performed a systematic review and meta-analysis of CCI score and a composite of poor outcomes through several databases.
resultsCompared to a CCI score of 0, a CCI score of 1-2 and CCI score of ≥3 was prognostically associated with mortality and associated with a composite of poor outcomes. Per point increase of CCI score also increased mortality risk by 16%. Moreover, a higher mean CCI score also significantly associated with mortality and disease severity.
conclusionCCI score should be utilized for risk stratifications of hospitalized COVID-19 patients.
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