Evidence map›Paper›PMID 33160926›Full record

ReviewPET clinics2021

Total-Body PET Imaging in Infectious Diseases.

Timothy J Henrich, Terry Jones, Denis Beckford-Vera, Patricia M Price, Henry F VanBrocklin

Open access · greenAbstract readReview
In one paragraph

Review in PET clinics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Nature communications · 2025
    Observational
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Advantages and Applications of Total-Body PET Scanning.Diagnostics (Basel, Switzerland) · 2022
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Timothy J HenrichDivision of Experimental Medicine, University of California San Francisco, 1001 Potrero Avenue, Building 3, Room 525A, San Francisco, CA 94110, USA. Electronic address: Timothy.Henrich@ucsf.edu.
Terry JonesDepartment of Radiology, University of California Davis Medical Center, Sacramento, CA, USA.
Denis Beckford-VeraDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.
Patricia M PriceDepartment of Surgery and Cancer, Imperial College, London, UK.
Henry F VanBrocklinDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.
University of California, San Francisco · USImperial College London · GBUniversity of California Davis Medical Center · USUniversity of California System · US

Funding

Delaney AIDS Research Enterprise to Cure HIVUM1AI126611 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DEEKS, STEVEN GRANT, PICKER, LOUIS J. · 2016 to 2020
$27.9M
In Vivo PET Imaging of HIV InfectionR01AI152932 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HENRICH, TIMOTHY JENSEN, HSUE, PRISCILLA Y. · 2020 to 2025
$3.7M
NIAID NIH HHS R01 AI152932NIAID NIH HHS UM1 AI126611
6 · The paper itself

Abstract

Total-body PET enables high-sensitivity imaging with dramatically improved signal-to-noise ratio. These enhanced performance characteristics allow for decreased PET scanning times acquiring data "total-body wide" and can be leveraged to decrease the amount of radiotracer required, thereby permitting more frequent imaging or longer imaging periods during radiotracer decay. Novel approaches to PET imaging of infectious diseases are emerging, including those that directly visualize pathogens in vivo and characterize concomitant immune responses and inflammation. Efforts to develop these imaging approaches are hampered by challenges of traditional imaging platforms, which may be overcome by novel total-body PET strategies.

Indexed as

Communicable DiseasesHumansPositron-Emission TomographySignal-To-Noise RatioTimeWhole Body ImagingCOVID-19Human immunodeficiency syndromeInfectious diseasesT cellsTotal-body PET

Identifiers

PMID33160926
PMCPMC10270309
OpenAlexW3096201199

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.