ArticleBiological psychiatry. Cognitive neuroscience and neuroimaging2021
Neural Oscillatory Abnormalities During Gaze Processing in Schizophrenia: Evidence of Reduced Theta Phase Consistency and Inter-areal Theta-Gamma Coupling.
Article in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Cognitive Mechanisms of Aberrant Self-Referential Social Perception in Psychosis and Bipolar Disorder: Insights From Computational Modeling.Schizophrenia bulletin · 2026Article
- Attenuated theta-band activity and cross-frequency coupling in schizophrenia during affective response inhibition.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025Article
- Response Monitoring Theta-Band Activities Across Emotional Contexts in Schizophrenia and Bipolar Spectrum Disorders.Biological psychiatry global open science · 2025Article
- Dynamic brain communication underlying face pareidolia in male schizophrenia.Schizophrenia (Heidelberg, Germany) · 2025Article
- Seeing things in psychosis: Reduced theta power in early neural responses to ambiguous visual stimuli predicts perceptual distortions.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025Article
- Fronto-occipital dyscommunication associates with brain hierarchy in schizophrenia.Communications biology · 2025Article
- Fixational eye movements and their associated evoked potentials during natural vision are altered in schizophrenia.Schizophrenia research. Cognition · 2024Article
- Real-time TMS-EEG for brain state-controlled research and precision treatment: a narrative review and guide.Journal of neural engineering · 2024Review
- Mutual information of multiple rhythms in schizophrenia.Brain structure & function · 2024Article
- Limited Consistency and Strength of Neural Oscillations During Sustained Visual Attention in Schizophrenia.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024Article
- Reductions in regional theta power and fronto-parietal theta-gamma phase-amplitude coupling during gaze processing in bipolar disorder.Psychiatry research. Neuroimaging · 2023Article
- Frequency-specific gaze modulation of emotional face processing in the human amygdala.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Article
- Unveiling the Associations between EEG Indices and Cognitive Deficits in Schizophrenia-Spectrum Disorders: A Systematic Review.Diagnostics (Basel, Switzerland) · 2022Review
- EEG alpha and theta signatures of socially and non-socially cued working memory in virtual reality.Social cognitive and affective neuroscience · 2022Article
- An Effortful Approach to Social Affiliation in Schizophrenia: Preliminary Evidence of Increased Theta and Alpha Connectivity during a Live Social Interaction.Brain sciences · 2021Article
- Sleep-Wake Rhythm and Oscillatory Pattern Analysis in a Multiple Hit Schizophrenia Rat Model (Wisket).Frontiers in behavioral neuroscience · 2021Article
- What Can Local Transfer Entropy Tell Us about Phase-Amplitude Coupling in Electrophysiological Signals?Entropy (Basel, Switzerland) · 2020Article
Corrections and comments
- Erratum issuedErratum.2024
Authors and funding
6 authors.
Funding
Abstract
backgroundAbnormal gaze discrimination in schizophrenia (SZ) is associated with impairment in social functioning, but the neural mechanisms remain unclear. Evidence suggests that local neural oscillations and inter-areal communication through neural synchronization are critical physiological mechanisms supporting basic and complex cognitive processes. The roles of these mechanisms in abnormal gaze processing in SZ have not been investigated. The present study examined local neural oscillations and connectivity between anterior and bilateral posterior brain areas during gaze processing.
methodsDuring electroencephalography recording, 28 participants with SZ and 34 healthy control participants completed a gaze discrimination task. Time-frequency decomposition of electroencephalography data was used to examine neural oscillatory power and intertrial phase consistency at bilateral posterior and midline anterior scalp sites. In addition, connectivity between these anterior and posterior sites, in terms of cross-frequency coupling between theta phase and gamma amplitude, was examined using the Kullback-Leibler Modulation Index.
resultsParticipants with SZ showed reduced total power of theta-band activity relative to healthy control participants at all sites examined. This group difference could be accounted for by reduced intertrial phase consistency of theta activity in SZ participants, which was related to reduced gaze discrimination accuracy in SZ. In addition, SZ participants exhibited reduced Kullback-Leibler indexing, both feedforward and feedback connectivity, between the posterior and anterior sites.
conclusionsThese findings suggest that abnormal theta phase consistency and dysconnection between posterior face processing and anterior areas may underlie gaze processing deficits in SZ.
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