Evidence map›Paper›PMID 33160840›Full record

ReviewTrends in immunology2020

Turning Discoveries into Treatments: Immunology in Africa.

Faith H A Osier, Henry C Mwandumba, Clive M Gray

Abstract readReview
In one paragraph

Review in Trends in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The African Light Source: history, context and future.Journal of synchrotron radiation · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Faith H A OsierCentre of Infectious Diseases, Heidelberg University Hospital, Heidelberg, Germany; KEMRI Wellcome Trust Research Programme, Centre for Geographic Medicine Research-Coast, Kilifi, Kenya. Electronic address: FOsier@kemri-wellcome.org.
Henry C MwandumbaMalawi Liverpool Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.
Clive M GrayDivision of Immunology, Institute of Infectious Disease and Molecular Medicine and Department of Pathology, University of Cape Town, Cape Town, South Africa.

Funding

Lung immune function in human TB infection and its perturbation by HIV-1.R01AI155319 · NIAID · CORNELL UNIVERSITY · PI MWANDUMBA, HENRY CHARLES, RUSSELL, DAVID G · 2020 to 2024
$3.3M
Impact of HIV exposure, feeding status, and microbiome on immune ontogeny and vaccine responses in infantsU01AI131302 · NIAID · STANFORD UNIVERSITY · PI BLISH, CATHERINE A, GRAY, CLIVE MAURICE · 2017 to 2021
$2.1M
MECHANISMS LEADING TO ADVERSE BIRTH OUTCOMES IN SOUTH AFRICAN HIV-INFECTED WOMENR01HD102050 · NICHD · UNIVERSITY OF CAPE TOWN · PI GRAY, CLIVE MAURICE, JASPAN, HEATHER BERYL · 2020 to 2024
$1.7M
Mechanisms by which trophoblasts recruit T cells to the placental villi during maternal HIV and CMV co-infectionR21HD103498 · NICHD · MAYO CLINIC ROCHESTER · PI CHAKRABORTY, RANA, GRAY, CLIVE MAURICE · 2020 to 2021
$390k
Medical Research Council MR/P020526/1NIAID NIH HHS R01 AI155319NIAID NIH HHS U01 AI131302NICHD NIH HHS R01 HD102050NICHD NIH HHS R21 HD103498NIH HHS AI155319NIH HHS R21 HD103498-01NIH HHS U01AI131302-01
6 · The paper itself

Abstract

An exemplar outcome of an immunology-based intervention is vaccine development; the current COVID-19 pandemic is a case in point. Can we build an immunology research ecosystem in Africa that nurtures discovery and enables translation? We see African immunologists as key agents of change and discuss obstacles and opportunities.

Indexed as

Allergy and ImmunologyDeveloping CountriesAfricaCOVID-19 VaccinesHumansSARS-CoV-2COVID-19 VaccinesAfrican scientistsfundingimmunologytrainingvaccines

Identifiers

PMID33160840
PMCPMC7879494

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.