ArticleRadiation oncology (London, England)2020
Technical note: factors affecting dose distribution in the overlap region of two-segment total body irradiation by helical tomotherapy.
Article in Radiation oncology (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 13 citations in OpenAlex.
- A simulation study of a novel spiral volumetric modulated arc therapy for enhanced dose delivery efficiency and quality in radiotherapy.Medical physics · 2026Article
- Dosimetric impact of port number in TomoDirect-based lower-body total body irradiation.Journal of applied clinical medical physics · 2026Article
- Dosimetric assessment of TomoDirect radiotherapy and TomoHelical radiotherapy in the clinical implementation of total skin irradiation.Frontiers in oncology · 2025Article
- Timing matters: diurnal spine length variation in pediatric patients during radiotherapy.Radiation oncology (London, England) · 2024Article
- Impact of delivery time factor on treatment time and plan quality in tomotherapy.Scientific reports · 2023Article
- Investigation of total skin helical tomotherapy using a 3D-printed total skin bolus.Biomedical engineering online · 2023Article
- Helical versus static approaches to delivering tomotherapy to the junctional target for patients taller than 135 cm undergoing total body irradiation.European journal of medical research · 2022Article
- Influencing Factors of Total Skin Irradiation With Helical Tomotherapy.Frontiers in oncology · 2022Article
- Spiral Computed Tomography in the Quantitative Measurement of the Adjacent Structure of the Left Atrial Appendage in Patients with Atrial Fibrillation.Journal of healthcare engineering · 2021Article
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
objectiveTo assess the effects of various treatment planning parameters to identify the optimal gap distance for precise two-segment total body irradiation (TBI) using helical tomotherapy (HT) with fixed jaw mode. METHODS AND MATERIALS: Data of a treatment plan for 8 acute leukemia patients (height range: 109-130 cm) were analyzed. All patients underwent total-body computed tomography (CT) with 5-mm slice thickness. A lead wire, placed at 10 cm above the patella, was used to mark the boundary between the two segments. Target volumes and organs at risk were delineated using a Varian Eclipse 10.0 physician's workstation. Different distances between the lead wire and the boundary of the two targets were used. CT images were transferred to the HT workstation to design the treatment plans, by adjusting parameters, including the field width (FW; 2.5 cm, and 5 cm), pitch (0.287 and 0.430), modulation factor (1.8). The plans were superimposed to analyze the dose distributions in the overlap region when varying target gap distances, FWs, pitches to determine the optimal combinations.
resultsThe pitch did not affect the dose distribution in the overlap region. The dose distribution in the overlap region was mostly homogeneous when the target gap distance was equal to the FW. Increased FW diminished the effect of the target gap distance on the heterogeneous index of the overlap region.
conclusionsIn two-segment TBI treatments by HT with Helix mode, a gap distance equal to the FW may achieve optimal dose distribution in the overlap region.
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