ArticleJournal of experimental botany2021
Reactive oxygen species coordinate the transcriptional responses to iron availability in Arabidopsis.
Article in Journal of experimental botany, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 33 citations in OpenAlex.
- Single-cell transcriptional decoding of iron deficiency responses in maize root tips.Plant cell reports · 2025Article
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- Genome-wide association study reveals effect of nsSNPs on candidate genes in rice during iron deficiency.Functional & integrative genomics · 2024Article
- Improved pokeweed genome assembly and early gene expression changes in response to jasmonic acid.BMC plant biology · 2024Article
- Micronutrient deficiency-induced oxidative stress in plants.Plant cell reports · 2024Review
- Brain Iron Metabolism, Redox Balance and Neurological Diseases.Antioxidants (Basel, Switzerland) · 2023Review
- Evidence ThatPlants (Basel, Switzerland) · 2023Article
- SEC14-GOLD protein PATELLIN2 binds IRON-REGULATED TRANSPORTER1 linking root iron uptake to vitamin E.Plant physiology · 2023Article
- Integration of reactive oxygen species and nutrient signalling to shape root system architecture.Plant, cell & environment · 2023Review
- GmABCG5, an ATP-binding cassette G transporter gene, is involved in the iron deficiency response in soybean.Frontiers in plant science · 2023Article
- Crosstalk Between Iron and Sulfur Homeostasis Networks inFrontiers in plant science · 2022Article
- Endophytic FungusFrontiers in plant science · 2022Article
- Mapping of the Quantitative Trait Loci and Candidate Genes Associated With Iron Efficiency in Maize.Frontiers in plant science · 2022Article
- The iron will of the research community: advances in iron nutrition and interactions in lockdown times.Journal of experimental botany · 2021Article
- Cross-Talks Between Macro- and Micronutrient Uptake and Signaling in Plants.Frontiers in plant science · 2021Review
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reactive oxygen species play a central role in the regulation of plant responses to environmental stress. Under prolonged iron (Fe) deficiency, increased levels of hydrogen peroxide (H2O2) initiate signaling events, resulting in the attenuation of Fe acquisition through the inhibition of FER-LIKE IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR (FIT). As this H2O2 increase occurs in a FIT-dependent manner, our aim was to understand the processes involved in maintaining H2O2 levels under prolonged Fe deficiency and the role of FIT. We identified the CAT2 gene, encoding one of the three Arabidopsis catalase isoforms, as regulated by FIT. CAT2 loss-of-function plants displayed severe susceptibility to Fe deficiency and greatly increased H2O2 levels in roots. Analysis of the Fe homeostasis transcription cascade revealed that H2O2 influences the gene expression of downstream regulators FIT, BHLH genes of group Ib, and POPEYE (PYE); however, H2O2 did not affect their upstream regulators, such as BHLH104 and ILR3. Our data shows that FIT and CAT2 participate in a regulatory loop between H2O2 and prolonged Fe deficiency.
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