Evidence map›Paper›PMID 33159619›Full record

ArticleGeneral thoracic and cardiovascular surgery2021

Autologous skeletal myoblast sheet implantation for pediatric dilated cardiomyopathy: A case report.

Kanta Araki, Masaki Taira, Shigeru Miyagawa, Tomomitsu Kanaya, Naoki Okuda, Koichi Toda, Toru Kuratani, Takayoshi Ueno, Yoshiki Sawa

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in General thoracic and cardiovascular surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kanta ArakiOsaka University Graduate School of Medicine, Department of Cardiovascular Surgery, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.ORCID http://orcid.org/0000-0003-1970-1846
Masaki TairaOsaka University Graduate School of Medicine, Department of Cardiovascular Surgery, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Shigeru MiyagawaOsaka University Graduate School of Medicine, Department of Cardiovascular Surgery, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Tomomitsu KanayaOsaka University Graduate School of Medicine, Department of Cardiovascular Surgery, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Naoki OkudaOsaka University Graduate School of Medicine, Department of Cardiovascular Surgery, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Koichi TodaOsaka University Graduate School of Medicine, Department of Cardiovascular Surgery, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Toru KurataniOsaka University Graduate School of Medicine, Department of Cardiovascular Surgery, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Takayoshi UenoOsaka University Graduate School of Medicine, Department of Cardiovascular Surgery, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Yoshiki SawaOsaka University Graduate School of Medicine, Department of Cardiovascular Surgery, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. sawa-p@surg1.med.osaka-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn children with dilated cardiomyopathy, heart transplantation is the last treatment option. However, new regenerative treatments, such as cell therapy, have attracted scientific attention. We have previously demonstrated the efficacy of autologous skeletal myoblast sheet implantation for treatment of ischemic and dilated cardiomyopathy in adults. Because of the mechanism underlying this cell therapy, a similar effectiveness is expected for patients with pediatric dilated cardiomyopathy. CASE: Herein, we describe the case of a child with dilated cardiomyopathy who underwent an autologous skeletal myoblast sheet implantation, which proved to be safe, and led to sustained maintenance and improvements in cardiac function and clinical status.

Indexed as

Cardiomyopathy, DilatedHeart TransplantationMyoblasts, SkeletalChildHumansTransplantation, AutologousAutologous skeletal myoblast sheetCell therapyMyocardial regenerationPediatric dilated cardiomyopathy

Identifiers

PMID33159619

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.