Evidence map›Paper›PMID 33159608›Full record

ReviewCurrent urology reports2020

Salvage Pelvic Lymph Node Dissection and Current State of Imaging for Recurrent Prostate Cancer: Does a Standard Exist?

Hannah McCloskey, Jesse Jacobs, Ibardo Zambrano, Theodore Moore, Amir H Khandani, Marc A Bjurlin

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current urology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hannah McCloskeyDepartment of Urology, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Jesse JacobsDepartment of Urology, University of North Carolina School of Medicine, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0002-3742-999X
Ibardo ZambranoDepartment of Urology, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Theodore MooreDepartment of Urology, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Amir H KhandaniDepartment of Radiology, Division of Molecular Imaging and Therapeutics (Mit), University of North Carolina, Chapel Hill, NC, USA.
Marc A BjurlinDepartment of Urology, University of North Carolina School of Medicine, Chapel Hill, NC, USA. marc_bjurlin@med.unc.edu.
University of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewWe aim to evaluate the efficacy of salvage lymph node dissection (SLND) for nodal recurrent prostate cancer after primary treatment. We also provide a review of the diagnostic performance of next-generation sequencing (next-generation imaging (NGI)) radiotracers in the salvage setting. RECENT

findingsMost studies evaluating SLND include a heterogeneous population with a small sample size and are retrospective in design. The 5-year clinical recurrence-free and cancer-specific survival following SLND are 26-52% and 57-89%, respectively, among prospective studies. NGI improves accuracy in detecting nodal recurrence compared to conventional CT, with PMSA PET-CT showing the most promise. However, limited studies exist comparing imaging modalities and performance is variable at low PSA values. SLND is a promising treatment option, but more prospective data are needed to determine the ideal surgical candidate and long-term oncologic outcomes. More studies comparing different NGI are needed to determine the best imaging modality in patients who may be candidates for salvage treatment.

Indexed as

HumansLymph Node ExcisionLymph NodesMagnetic Resonance ImagingMaleNeoplasm Recurrence, LocalPatient SelectionPelvisPositron Emission Tomography Computed TomographyProspective StudiesProstatectomyProstatic NeoplasmsSalvage TherapyBiochemical recurrenceImagingLymph node dissectionMRIPET-CTPET-MRIProstate cancer

Identifiers

PMID33159608
OpenAlexW3095286343

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.