Evidence map›Paper›PMID 33159516›Full record

ArticleThe Gerontologist2021

Feasibility Trial of a Mind-Body Activity Pain Management Program for Older Adults With Cognitive Decline.

Ryan A Mace, Melissa V Gates, Paula J Popok, Ron Kulich, Yakeel T Quiroz, Ana-Maria Vranceanu

2 registry-linked trialsAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Gerontologist, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05373745 nacompletednot on this mapstarted 2022, after this paper: background citation

Addressing the Chronic Pain-Early Cognitive Decline Comorbidity Among Older Adults; The Active Brains Study

TypeinterventionalSponsorMassachusetts General HospitalRan2022 to 2026Enrolled267ConditionsChronic Pain, Mild Cognitive Impairment, Older Adults, Physical ActivityArmsActive Brains 1, Active Brains 2
NCT06246929 narecruitingnot on this mapstarted 2025, after this paper: background citation

Comorbidity of Chronic Pain and Early Cognitive Decline Among Older, Community-Based Black Adults: Comparative Effectiveness of Mindfulness-Based Cognitive Therapy With Walking (MBCT+w) vs Active Living Every Day (ALED)

TypeinterventionalSponsorMassachusetts General HospitalRan2025 to 2028Enrolled400ConditionsChronic Pain, Physical Activity, Older Adults, Mild Cognitive ImpairmentArmsMBCT+w, ALED
3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ryan A MaceIntegrated Brain Health Clinical and Research Program, Massachusetts General Hospital, Boston, USA.
Melissa V GatesIntegrated Brain Health Clinical and Research Program, Massachusetts General Hospital, Boston, USA.
Paula J PopokIntegrated Brain Health Clinical and Research Program, Massachusetts General Hospital, Boston, USA.
Ron KulichHarvard Medical School, Boston, Massachusetts, USA.
Yakeel T QuirozHarvard Medical School, Boston, Massachusetts, USA.
Ana-Maria VranceanuIntegrated Brain Health Clinical and Research Program, Massachusetts General Hospital, Boston, USA.ORCID 0000-0003-3994-6488

Funding

Integrating Mind Body Skills with Physical Activity to Improve Pain Outcomes in Patients with Heterogeneous Chronic Pain ConditionsR34AT009356 · NCCIH · MASSACHUSETTS GENERAL HOSPITAL · PI VRANCEANU, ANA-MARIA · 2017 to 2019
$1.2M
NCCIH NIH HHS R34 AT009356
6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe relationship between chronic pain (CP) and cognitive decline (CD) is bidirectional among older adults. The CP-CD comorbidity can progressively worsen cognitive, physical, emotional, and social functioning with aging. We explored the feasibility and outcomes associated with 2 mind-body activity programs for CP and CD that focus on increasing walking using time goals (Active Brains) or step-count reinforced via Fitbit (Active Brains-Fitbit). RESEARCH DESIGN AND

methodsOlder adults with CP and CD participated in a nonrandomized open pilot of Active Brains (n = 6) and Active Brains-Fitbit (n = 6) followed by exit interviews. Quantitative analysis explored feasibility markers and signals of improvement on physical, cognitive, and emotional function, as well as additional program targets. Qualitative analyses were predominantly deductive and applied the Framework Method to enhance the programs and methodology.

resultsBoth programs met a priori feasibility benchmarks. We found within-group improvements for pain intensity, pain-specific coping, physical function, and cognitive function in both programs. Exit interviews confirmed high satisfaction with both programs. DISCUSSION AND IMPLICATIONS: Our mixed-methods data provide preliminary evidence of feasibility, showed promise for improving outcomes, and yielded critical information to further enhance the programs. We discuss "lessons learned" and future directions.

Indexed as

Chronic PainCognitive DysfunctionAgedFeasibility StudiesHumansPain ManagementWalkingCognitionMind–bodyPain managementPilot studyWalking

Identifiers

PMID33159516
PMCPMC8679005

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.