Evidence map›Paper›PMID 33159300›Full record

ArticleCell biochemistry and biophysics2021

Simultaneous Determination of Human Erythrocyte Deformability and Adhesion Energy: A Novel Approach Using a Microfluidic Chamber and the "Glass Effect".

Carolina M Londero, Bibiana D Riquelme

Abstract read
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In one paragraph

Article in Cell biochemistry and biophysics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Carolina M LonderoÁrea Física, Facultad de Cs Bioquímicas y Farmacéuticas (UNR), Suipacha 531, 20000, Rosario, Santa Fe, Argentina.
Bibiana D RiquelmeÁrea Física, Facultad de Cs Bioquímicas y Farmacéuticas (UNR), Suipacha 531, 20000, Rosario, Santa Fe, Argentina. briquel@fbioyf.unr.edu.ar.ORCID http://orcid.org/0000-0003-0606-5713
National University of Rosario · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The simultaneous determination of adhesion and deformability parameters of erythrocytes was carried out through a microfluidic device, which uses an inverted optical microscope with new image acquisition and analysis technologies. Also, an update of the models describing erythrocyte adhesion and deformation was proposed. Measurements were carried out with red blood cells suspended in saline solution with human serum albumin at different concentrations. Erythrocytes adhered to a glass surface were subjected to different low shear stress (from 0.04 to 0.25 Pa), causing cellular deformation and dissociation. The maximum value obtained of the erythrocyte deformability index was 0.3, and that of the adhesion energy per unit area was 1.1 × 10

Indexed as

Erythrocyte DeformabilityMicrofluidicsAdultCell AdhesionErythrocytesGlassHumansImage Processing, Computer-AssistedLab-On-A-Chip DevicesLigandsLipid BilayersPressureSerum Albumin, HumanShear StrengthStress, MechanicalViscosityLigandsLipid BilayersSerum Albumin, HumanHemorheologyMicrofluidic chamberRed blood cell adhesionRed blood cell deformation

Identifiers

PMID33159300
OpenAlexW3095581860

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.