Evidence map›Paper›PMID 33159263›Full record

SynthesisActa parasitologica2021

The Experimental Role of Medicinal Plants in Treatment of Toxoplasma gondii Infection: A Systematic Review.

Kourosh Cheraghipour, Leila Masoori, Behrooz Ezzatpour, Mona Roozbehani, Ali Sheikhian, Vahid Malekara, Massumeh Niazi, Omid Mardanshah, Kobra Moradpour, Hossein Mahmoudvand

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Acta parasitologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Therapeutic effect of baicalein as an antiparasitic agent againstJournal of Zhejiang University. Science. B · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Veterinary world · 2024
    Article
  10. Article
  11. Article
  12. The effect of infection withArchives of Razi Institute · 2024
    Article
  13. Review
  14. Article
  15. Immune-enhancing activity ofAnnals of medicine and surgery (2012) · 2023
    Article
  16. Potent In Vitro and In Vivo Effects ofTropical medicine and infectious disease · 2023
    Article
  17. Evaluation of the Anti-Antibiotics (Basel, Switzerland) · 2023
    Article
  18. Article
  19. The role ofFrontiers in cellular and infection microbiology · 2023
    Article
  20. Potential effects of alpha-pinene, a monoterpene commonly found in essential oils againstJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Kourosh CheraghipourRazi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
Leila MasooriRazi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
Behrooz EzzatpourRazi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
Mona RoozbehaniDepartment of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Ali SheikhianRazi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
Vahid MalekaraRazi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
Massumeh NiaziStudent Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran.
Omid MardanshahDepartment of Laboratory Sciences, School of Medical Sciences, Sirjan Faculty of Medical Sciences, Kerman, Iran.
Kobra MoradpourLorestan University of Medical Sciences, Khorramabad, Iran.
Hossein MahmoudvandRazi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran. dmahmodvand@gmail.com.ORCID http://orcid.org/0000-0003-4194-393X
Lorestan University of Medical Sciences · IRIran University of Medical Sciences · IRKerman University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundToxoplasma gondii is the global protozoa that could cause contamination in warm-blooded animals and is considered among the opportunistic pathogens in immunocompromised patients. Among the people at risk, toxoplasmosis infection can lead to the incidence of severe clinical manifestations, encephalitis, chorioretinitis, and even death. PURPOSE: The present research is focused on the new research for the treatment of toxoplasmosis parasitic disease using medicinal herbs.

methodsThe search was performed in five English databases, including Scopus, PubMed, Web of Science, EMBASE, and Google Scholar up from 2010 to December 2019. Studies in any language were entered in the searching step if they had an English abstract. The words and terms were used as a syntax with specific tags of each database.

resultsOut of 1832 studies, 36 were eligible to be reviewed. The findings showed that 17 studies (47%) were performed in vitro, 14 studies (39%) in vivo, and 5 studies (14%) both in vivo and in vitro.

conclusionThe studies showed that the plant extracts can be a good alternative in reducing the toxoplasmosis effects in the host and the herbal extracts can be used to produce natural product-based drugs affecting toxoplasmosis with fewer side-effects than synthetic drugs.

Indexed as

Plants, MedicinalToxoplasmaToxoplasmosisAnimalsHumansImmunocompromised HostPlant ExtractsPlant ExtractsHerbal medicineMedicinal plantsSystematic reviewToxoplasma gondiiTreatment

Identifiers

PMID33159263
OpenAlexW3095677460

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.