ArticleEuropean biophysics journal : EBJ2020
Analysis of nonideality: insights from high concentration simulations of sedimentation velocity data.
Article in European biophysics journal : EBJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Facilitating the simulation of sedimentation velocity data: new features of SViMULATE.European biophysics journal : EBJ · 2025Article
- A scaling relationship between thermodynamic and hydrodynamic interactions in protein solutions.Biophysical journal · 2024Article
- Application of artificial neural network for the mechano-bactericidal effect of bioinspired nanopatterned surfaces.European biophysics journal : EBJ · 2024Article
- Hydrodynamic and thermodynamic analysis of PEGylated human serum albumin.Biophysical journal · 2024Article
- BASIS: BioAnalysis SEDFIT integrated software for cGMP analysis of SV-AUC data.European biophysics journal : EBJ · 2024Article
- Versatile Capillary Cells for Handling Concentrated Samples in Analytical Ultracentrifugation.Analytical chemistry · 2024Article
- Strong non-ideality effects at low protein concentrations: considerations for elongated proteins.European biophysics journal : EBJ · 2023Article
- Simulation of Gilbert theory for self-association in sedimentation velocity experiments: a guide to evaluate best fitting models.European biophysics journal : EBJ · 2023Article
- Comparative Thermodynamics of the Reversible Self-Association of Therapeutic mAbs Reveal Opposing Roles for Linked Proton- and Ion-Binding Events.Pharmaceutical research · 2023Article
- The Relationship between Protein-Protein Interactions and Liquid-Liquid Phase Separation for Monoclonal Antibodies.Molecular pharmaceutics · 2023Article
- Solution Structural Studies of Pre-amyloid Oligomer States of the Biofilm Protein Aap.Journal of molecular biology · 2022Article
- Energetic Dissection of Mab-Specific Reversible Self-Association Reveals Unique Thermodynamic Signatures.Pharmaceutical research · 2021Article
- Analytical ultracentrifugation: still the gold standard that offers multiple solutions.European biophysics journal : EBJ · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Aviv fluorescence detection system (Aviv-FDS) has allowed the performance of sedimentation velocity experiments on therapeutic antibodies in highly concentrated environments like formulation buffers and serum. Methods were implemented in the software package SEDANAL for the analysis of nonideal, weakly associating AUC data acquired on therapeutic antibodies and proteins (Wright et al. Eur Biophys J 47:709-722, 2018, Anal Biochem 550:72-83, 2018). This involved fitting both hydrodynamic, k
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