ArticleSleep2021
Changes in EEG permutation entropy in the evening and in the transition from wake to sleep.
Article in Sleep, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Caffeinated Brain Part 2: The Effect of Caffeine on Sleep-Related Electroencephalography (EEG)-A Systematic and Mechanistic Review.Nutrients · 2026Pooled it
- The entropic brain today.Brain : a journal of neurology · 2026Review
- Reframing "paradoxical" excitation: disentangling electroencephalogram complexity and entropy reveals resting-state dynamics associated with propofol susceptibility in healthy adults.British journal of anaesthesia · 2026Article
- Prediction of cognitive impairment in epilepsy with spike-and-wave activation in sleep based on EEG.Therapeutic advances in neurological disorders · 2026Article
- Orexin effect on physiological pulsations of the human brain.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Entropy of difference works similarly to permutation entropy for the assessment of anesthesia and sleep EEG despite the lower computational effort.Journal of clinical monitoring and computing · 2025Article
- A Permutation Entropy Method for Sleep Disorder Screening.Brain sciences · 2025Article
- Competitive roles of slow/delta oscillation-nesting-mediated sleep disruption under acute methamphetamine exposure in monkeys.Journal of Zhejiang University. Science. B · 2025Article
- A novel stroke classification model based on EEG feature fusion.Scientific reports · 2025Article
- Wavelet Entropy Analysis of Electroencephalogram Signals During Wake and Different Sleep Stages in Patients with Insomnia Disorder.Nature and science of sleep · 2024Article
- Functional hierarchies in brain dynamics characterized by signal reversibility in ferret cortex.PLoS computational biology · 2024Article
- Entropy in scalp EEG can be used as a preimplantation marker for VNS efficacy.Scientific reports · 2023Article
- Article
- Neural complexity is a common denominator of human consciousness across diverse regimes of cortical dynamics.Communications biology · 2022Article
- Clinical features and power spectral entropy of electroencephalography in Wilson's disease with dystonia.Brain and behavior · 2022Article
- Brain entropy, fractal dimensions and predictability: A review of complexity measures for EEG in healthy and neuropsychiatric populations.The European journal of neuroscience · 2022Review
- Estimating Permutation Entropy Variability via Surrogate Time Series.Entropy (Basel, Switzerland) · 2022Article
- The effect of age on electroencephalogram measures of anesthesia hypnosis: A comparison of BIS, Alpha Power, Lempel-Ziv complexity and permutation entropy during propofol induction.Frontiers in aging neuroscience · 2022Article
- Nonlinear EEG signatures of mind wandering during breath focus meditation.Current research in neurobiology · 2022Article
- Multi-Scale Permutation Entropy: A Potential Measure for the Impact of Sleep Medication on Brain Dynamics of Patients with Insomnia.Entropy (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
6 authors.
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Abstract
Quantifying the complexity of the EEG signal during prolonged wakefulness and during sleep is gaining interest as an additional mean to characterize the mechanisms associated with sleep and wakefulness regulation. Here, we characterized how EEG complexity, as indexed by Multiscale Permutation Entropy (MSPE), changed progressively in the evening prior to light off and during the transition from wakefulness to sleep. We further explored whether MSPE was able to discriminate between wakefulness and sleep around sleep onset and whether MSPE changes were correlated with spectral measures of the EEG related to sleep need during concomitant wakefulness (theta power-Ptheta: 4-8 Hz). To address these questions, we took advantage of large datasets of several hundred of ambulatory EEG recordings of individual of both sexes aged 25-101 years. Results show that MSPE significantly decreases before light off (i.e. before sleep time) and in the transition from wakefulness to sleep onset. Furthermore, MSPE allows for an excellent discrimination between pre-sleep wakefulness and early sleep. Finally, we show that MSPE is correlated with concomitant Ptheta. Yet, the direction of the latter correlation changed from before light-off to the transition to sleep. Given the association between EEG complexity and consciousness, MSPE may track efficiently putative changes in consciousness preceding sleep onset. An MSPE stands as a comprehensive measure that is not limited to a given frequency band and reflects a progressive change brain state associated with sleep and wakefulness regulation. It may be an effective mean to detect when the brain is in a state close to sleep onset.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.