Evidence map›Paper›PMID 33159170›Full record

ReviewNature reviews. Urology2020

Animal models of naturally occurring stone disease.

Ashley Alford, Eva Furrow, Michael Borofsky, Jody Lulich

Open access · greenAbstract readReview
In one paragraph

Review in Nature reviews. Urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 36 citations in OpenAlex.

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  16. An Improved Model for Biogenic Ammonium Urate.Crystal growth & design · 2023
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ashley AlfordUniversity of Minnesota Medical Center, Department of Urology, Minneapolis, MN, USA. aalford@umn.edu.ORCID 0000-0001-9529-8265
Eva FurrowUniversity of Minnesota College of Veterinary Medicine, Department of Veterinary Clinical Sciences, St Paul, MN, USA.ORCID 0000-0002-7339-2354
Michael BorofskyUniversity of Minnesota Medical Center, Department of Urology, Minneapolis, MN, USA.
Jody LulichUniversity of Minnesota College of Veterinary Medicine, Department of Veterinary Clinical Sciences, St Paul, MN, USA.ORCID 0000-0002-2338-1569
University of Minnesota · USUniversity of Minnesota Medical Center · US

Funding

The role of zinc transporters and dietary zinc in calcium oxalate urolithiasisK01OD019912 · OD · UNIVERSITY OF MINNESOTA · PI FURROW, EVA · 2015 to 2021
$760k
NIH HHS K01 OD019912
6 · The paper itself

Abstract

The prevalence of urolithiasis in humans is increasing worldwide; however, non-surgical treatment and prevention options remain limited despite decades of investigation. Most existing laboratory animal models for urolithiasis rely on highly artificial methods of stone induction and, as a result, might not be fully applicable to the study of natural stone initiation and growth. Animal models that naturally and spontaneously form uroliths are an underused resource in the study of human stone disease and offer many potential opportunities for improving insight into stone pathogenesis. These models include domestic dogs and cats, as well as a variety of other captive and wild species, such as otters, dolphins and ferrets, that form calcium oxalate, struvite, uric acid, cystine and other stone types. Improved collaboration between urologists, basic scientists and veterinarians is warranted to further our understanding of how stones form and to consider possible new preventive and therapeutic treatment options.

Indexed as

CatsDisease Models, AnimalDogsDolphinsFerretsOttersAnimalsBiomedical ResearchCalcium OxalateCystineGenetic Predisposition to DiseaseHyperuricemiaRisk FactorsStruviteUric AcidUrolithiasisCalcium OxalateCystineStruviteUric Acid

Identifiers

PMID33159170
PMCPMC9254658
OpenAlexW3094931105

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.