Evidence map›Paper›PMID 33158999›Full record

ArticlemBio2020

Long-Term Modeling of SARS-CoV-2 Infection of

Siyuan Hao, Kang Ning, Cagla Aksu Kuz, Kai Vorhies, Ziying Yan, Jianming Qiu

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 109 citations in OpenAlex.

  1. Article
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  12. Frontiers in cell and developmental biology · 2025
    Article
  13. Review
  14. Article
  15. Cell Culture Differentiation and Proliferation Conditions Influence theAmerican journal of respiratory cell and molecular biology · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Siyuan HaoDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Kang NingDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Cagla Aksu KuzDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Kai VorhiesDepartment of Anatomy and Cell Biology, University of Iowa, Iowa City, Iowa, USA.
Ziying YanDepartment of Anatomy and Cell Biology, University of Iowa, Iowa City, Iowa, USA ziying-yan@uiowa.edu jqiu@kumc.edu.
Jianming QiuDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA ziying-yan@uiowa.edu jqiu@kumc.edu.ORCID 0000-0001-9850-1695
University of Kansas Medical Center · USUniversity of Iowa · US

Funding

Vector Core-Core 2P30DK054759 · NIDDK · UNIVERSITY OF IOWA · PI Amy Leanne Ryan · 1998 to 2026
$30.5M
Molecular Regulation of Cell Development and Differentiation Phase III COBREP30GM122731 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI ABRAHAMSON, DALE R · 2017 to 2021
$5.6M
Viral and Host Determinants of Parvovirus ReplicationR01AI150877 · NIAID · UNIVERSITY OF KANSAS MEDICAL CENTER · PI QIU, JIANMING · 2020 to 2024
$2.4M
Mechanisms Underlying the Transduction Polarity of AAV in Polarized Human Airway EpitheliumR21AI151542 · NIAID · UNIVERSITY OF KANSAS MEDICAL CENTER · PI QIU, JIANMING, YAN, ZIYING · 2020 to 2021
$435k
Human bocavirus 1 (HBoV1) capsid entry and intracellular trafficking of polarized human airway epitheliumR21AI139572 · NIAID · UNIVERSITY OF KANSAS MEDICAL CENTER · PI QIU, JIANMING, YAN, ZIYING · 2018 to 2019
$434k
NIAID NIH HHS R01 AI150877NIAID NIH HHS R21 AI139572NIAID NIH HHS R21 AI151542NIDDK NIH HHS P30 DK054759NIGMS NIH HHS P30 GM122731
6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replicates throughout human airways. The polarized human airway epithelium (HAE) cultured at an airway-liquid interface (HAE-ALI) is an

Indexed as

Models, BiologicalBetacoronavirusBronchiCells, CulturedEpithelial CellsHumansKineticsRespiratory MucosaSARS-CoV-2Viral LoadViral TropismVirus ReleaseVirus Replicationairway epithelial damageepithelial damagehuman airway epitheliumlong-term infectionrecurrent infectionSARS-CoV-2

Identifiers

PMID33158999
PMCPMC7649230
OpenAlexW3096665612

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.