Evidence map›Paper›PMID 33158886›Full record

ArticleApplied and environmental microbiology2021

Bacterial-Like Nonribosomal Peptide Synthetases Produce Cyclopeptides in the Zygomycetous Fungus Mortierella alpina.

Jacob M Wurlitzer, Aleksa Stanišić, Ina Wasmuth, Sandra Jungmann, Dagmar Fischer, Hajo Kries, Markus Gressler

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 47 citations in OpenAlex.

  1. Genetic Dereplication of MultipleJournal of natural products · 2026
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  3. Review
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  7. Article
  8. Review
  9. A genetic tool to express long fungal biosynthetic genes.Fungal biology and biotechnology · 2023
    Article
  10. Review
  11. Article
  12. Regulation of the Leucine Metabolism inJournal of fungi (Basel, Switzerland) · 2022
    Article
  13. Influence ofFrontiers in microbiology · 2022
    Article
  14. New Scabimycins A-C Isolated fromMolecules (Basel, Switzerland) · 2021
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jacob M WurlitzerDepartment of Pharmaceutical Microbiology, Leibniz Institute for Natural Product Research and Infection Biology (Hans Knöll Institute), Friedrich Schiller University, Jena, Germany.
Aleksa StanišićJunior Research Group Biosynthetic Design of Natural Products, Leibniz Institute for Natural Product Research and Infection Biology (Hans Knöll Institute), Jena, Germany.
Ina WasmuthDepartment of Pharmaceutical Microbiology, Leibniz Institute for Natural Product Research and Infection Biology (Hans Knöll Institute), Friedrich Schiller University, Jena, Germany.
Sandra JungmannPharmaceutical Technology and Biopharmacy, Friedrich Schiller University Jena, Jena, Germany.
Dagmar FischerPharmaceutical Technology and Biopharmacy, Friedrich Schiller University Jena, Jena, Germany.
Hajo KriesJunior Research Group Biosynthetic Design of Natural Products, Leibniz Institute for Natural Product Research and Infection Biology (Hans Knöll Institute), Jena, Germany.
Markus GresslerDepartment of Pharmaceutical Microbiology, Leibniz Institute for Natural Product Research and Infection Biology (Hans Knöll Institute), Friedrich Schiller University, Jena, Germany markus.gressler@leibniz-hki.de.ORCID 0000-0001-5669-7618
Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI) · DEFriedrich Schiller University Jena · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungi are traditionally considered a reservoir of biologically active natural products. However, an active secondary metabolism has long not been attributed to early-diverging fungi such as

Indexed as

Fungal ProteinsMortierellaPeptides, CyclicPeptide SynthasesPhylogenyFungal Proteinsnon-ribosomal peptide synthasePeptides, CyclicPeptide Synthasesadenylation domaincyclopeptidehorizontal gene transferMortierellalesNRPSzygomycetes

Identifiers

PMID33158886
PMCPMC7848919
OpenAlexW3096021740

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.