ArticleInternational journal of gynecological cancer : official journal of the International Gynecological Cancer Society2021
Longitudinal patient-reported outcomes and restrictive opioid prescribing after minimally invasive gynecologic surgery.
Article in International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 13 citations in OpenAlex.
- Eliminating opioid prescriptions from outpatient minimally invasive gynecologic surgery: a randomized trial.Nature medicine · 2026Trial
- Evaluation of a tiered opioid prescription algorithm in an ERAS pathway: exploring opportunities for further refinement.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2024Article
- Validation of uterine artery embolization before surgical laparoscopic myomenucleation compared to single surgical laparoscopic myomenucleation for the treatment of large fibroids and uterus myomatosus.Frontiers in medicine · 2023Article
- A prospective feasibility study evaluating the 5x-multiplier to standardize discharge prescriptions in cancer surgery patients.Surgery open science · 2022Article
- Incidence of acute kidney injury after open gynecologic surgery in an enhanced recovery after surgery pathway.Gynecologic oncology · 2021Article
- Impact of a tiered discharge opioid algorithm on prescriptions and patient-reported outcomes after open gynecologic surgery.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2021Article
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13 authors at 1 institution in 1 country.
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Abstract
objectiveTo determine post-discharge patient-reported symptoms before and after implementation of restrictive opioid prescribing among women undergoing minimally invasive gynecologic surgery.
methodsWe compared clinical outcomes and symptom burden among a cohort of 389 women undergoing minimally invasive gynecologic surgery at a single institution before and after implementation of a restrictive opioid prescribing quality improvement initiative in July 2018. Post-discharge symptom burdens were collected up to 42 days after discharge using the MD Anderson Symptom Inventory and analyzed using linear mixed effects models.
resultsThe majority of women included in this study were white non-smokers and the median age was 55 (range 23-83). Most women underwent hysterectomy (64%), had surgery for malignancy (71%), and were discharged from the hospital on the day of surgery (65%). Women in the restrictive opioid prescribing group had a median reduction in morphine equivalent dose prescribed at discharge of 83%, corresponding to a median reduction in 25 tablets of 5 mg oxycodone per person. There was no difference between opioid prescribing groups in either the rate of refill requests (P=1) or hospital re-admission (P=1) up to 30 days after discharge. After adjustment for co-variates, there was no statistically significant difference in post-discharge symptom burden including patient-reported pain (P=0.08), sleep (P=0.30), walking interference (P=0.64), activity interference (P=0.12), or affective interference (P=0.67). There was a trend toward less reported constiptation in the restrictive opioid prescribing group that did not reach statistical significance (P=0.05).
conclusionWe found that restrictive post-operative opioid prescribing was not associated with differences in longitudinal symptom burden among women undergoing minimally invasive gynecologic surgery. These results provide the most comprehensive picture to date of post-operative symptom recovery under different opioid prescribing approaches, lending additional support for existing recommendations to reduce opioid prescribing following gynecologic surgery.
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