Evidence map›Paper›PMID 33158599›Full record

ArticleSeminars in perinatology2020

Infection control and other stewardship strategies in late onset sepsis, necrotizing enterocolitis, and localized infection in the neonatal intensive care unit.

Samia Aleem, Megan Wohlfarth, C Michael Cotten, Rachel G Greenberg

Open access · greenAbstract read
In one paragraph

Article in Seminars in perinatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Samia AleemDepartment of Pediatrics, Duke University, Durham, NC, USA.
Megan WohlfarthNC School of Science and Mathematics, Durham, NC.
C Michael CottenDepartment of Pediatrics, Duke University, Durham, NC, USA.
Rachel G GreenbergDepartment of Pediatrics, Duke University, Durham, NC, USA; Duke Clinical Research Institute, Durham, NC, USA. Electronic address: rachel.greenberg@duke.edu.
Duke University · USClinical Research Institute · USNorth Carolina School of Science and Mathematics · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Suspected or proven late onset sepsis, necrotizing enterocolitis, urinary tract infections, and ventilator associated pneumonia occurring after the first postnatal days contribute significantly to the total antibiotic exposures in neonatal intensive care units. The variability in definitions and diagnostic criteria in these conditions lead to unnecessary antibiotic use. The length of treatment and choice of antimicrobial agents for presumed and proven episodes also vary among centers due to a lack of supportive evidence and guidelines. Implementation of robust antibiotic stewardship programs can encourage compliance with appropriate dosages and narrow-spectrum regimens.

Indexed as

Enterocolitis, NecrotizingSepsisAnti-Bacterial AgentsHumansInfant, NewbornInfection ControlIntensive Care Units, NeonatalAnti-Bacterial Agents

Identifiers

PMID33158599
PMCPMC7550069
OpenAlexW3092197699

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.