Evidence map›Paper›PMID 33158508›Full record

SynthesisJournal of pediatric surgery2021

Management of intussusception in children: A systematic review.

Lorraine I Kelley-Quon, L Grier Arthur, Regan F Williams, Adam B Goldin, Shawn D St Peter, Alana L Beres, Yue-Yung Hu, Elizabeth J Renaud, Robert Ricca, Mark B Slidell and 13 more

Registry-linked trialOpen access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Journal of pediatric surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06351163 (Minimally Invasive Surgical Management for Pediatric Intussusception), which is not on this map. Cited by 59 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 4 pooled it
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06351163 completednot on this map

Minimally Invasive Surgical Management for Pediatric Intussusception: A Retrospective Cohort Study on the Long-Term Outcome

TypeobservationalSponsorNational Children's Hospital, VietnamRan2016 to 2024Enrolled181ConditionsIntussusceptionArmsLaparoscopic reduction, Transumbilical mini-open reduction
3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 4 syntheses or guidelines pooled it, 127 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 20 institutions in 1 country.

Lorraine I Kelley-QuonDivision of Pediatric Surgery, Children's Hospital Los Angeles and the Department of Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA; Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA. Electronic address: lkquon@chla.usc.edu.
L Grier ArthurDivision of Pediatric Surgery, St. Christopher's Hospital for Children, Philadelphia, PA.
Regan F WilliamsDivision of Pediatric Surgery, Le Bonheur Children's Hospital, University of Tennessee Health Science Center, Memphis, TN.
Adam B GoldinDivision of Pediatric General and Thoracic Surgery, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, WA.
Shawn D St PeterDepartment of Surgery, Children's Mercy Hospital, Kansas City, MO.
Alana L BeresDivision of Pediatric General, Thoracic and Fetal Surgery, University of California, Davis, CA.
Yue-Yung HuDivision of Pediatric Surgery, Ann & Robert H. Lurie Children's Hospital, Northwestern University Feinberg School of Medicine, Chicago, IL.
Elizabeth J RenaudAlpert Medical School at Brown University, Hasbro Children's Hospital, Providence, RI.
Robert RiccaDivision of Pediatric Surgery, Naval Medical Center Portsmouth, Portsmouth, Virginia.
Mark B SlidellSection of Pediatric Surgery, The University of Chicago Medicine, Comer Children's Hospital, Chicago, IL.
Amy TaylorTexas Medical Center Library, Houston, TX.
Caitlin A SmithDivision of Pediatric General and Thoracic Surgery, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, WA.
Doug MiniatiDivision of Pediatric Surgery, Kaiser Permanente Roseville Women and Children's Center, Roseville, CA.
Juan E SolaDivision of Pediatric Surgery, University of Miami Miller School of Medicine, Miami, FL.
Patricia ValusekPediatric Surgical Associates, Ltd., Children's Minnesota, Minneapolis, MN.
Loren BermanDivision of Pediatric surgery, Department of Surgery, Nemours-AI DuPont Hospital for Children and Sidney Kimmel Medical College at Thomas Jefferson University, Wilmington, DE.
Mehul V RavalDivision of Pediatric Surgery, Ann & Robert H. Lurie Children's Hospital, Northwestern University Feinberg School of Medicine, Chicago, IL.
Ankush GosainDivision of Pediatric Surgery, Le Bonheur Children's Hospital, University of Tennessee Health Science Center, Memphis, TN.; Children's Foundation Research Institute, Le Bonheur Children's Hospital, Memphis, TN.
Matthew B DellingerDivision of Pediatric General and Thoracic Surgery, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, WA.
Stig SømmeDivision of Pediatric Surgery, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, CO.
Cynthia D DownardDivision of Pediatric Surgery, Hiram C. Polk, Jr, MD Department of Surgery, University of Louisville, Louisville, KY.
Jarod P McAteerAlaska Pediatric Surgery, Anchorage, AK.
Akemi KawaguchiDepartment of Pediatric Surgery, University of Texas McGovern Medical School and Children's Memorial Hermann Hospital, Houston, TX.
University of Tennessee Health Science Center · USUniversity of Washington · USBrown University · USChildren's Hospital of Los Angeles · USChildren's Mercy Hospital · USChildren's Minnesota · USComer Children's Hospital · USDuPont (United States) · USKaiser Permanente Roseville Medical Center · USLurie Children's Hospital · USMemorial Hermann · USNaval Medical Center Portsmouth · USNorthwestern University · USSeattle Children's Hospital · USSt. Christopher's Hospital for Children · USTexas Medical Center · USUniversity of California, Davis · USUniversity of Colorado Denver · USUniversity of Louisville · USUniversity of Miami · US

Funding

Mentored Career DevelopmentKL2TR001854 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Elizabeth Rhea Erwin Burner, Amy Elizabeth West · 2016 to 2026
$9.0M
NCATS NIH HHS KL2 TR001854
6 · The paper itself

Abstract

objectiveThe goal of this systematic review by the American Pediatric Surgical Association Outcomes and Evidence-Based Practice Committee was to develop recommendations for the management of ileocolic intussusception in children.

methodsThe ClinicalTrials.gov, Embase, PubMed, and Scopus databases were queried for literature from January 1988 through December 2018. Search terms were designed to address the following topics in intussusception: prophylactic antibiotic use, repeated enema reductions, outpatient management, and use of minimally invasive techniques for children with intussusception. The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines were followed. Consensus recommendations were derived based on the best available evidence.

resultsA total of 83 articles were analyzed and included for review. Prophylactic antibiotic use does not decrease complications after radiologic reduction. Repeated enema reductions may be attempted when clinically appropriate. Patients can be safely observed in the emergency department following enema reduction of ileocolic intussusception, avoiding hospital admission. Laparoscopic reduction is often successful.

conclusionsRegarding intussusception in hemodynamically stable children without critical illness, pre-reduction antibiotics are unnecessary, non-operative outpatient management should be maximized, and minimally invasive techniques may be used to avoid laparotomy. LEVEL OF EVIDENCE: Level 3-5 (mainly level 3-4) TYPE OF STUDY: Systematic Review of level 1-4 studies.

Indexed as

Emergency Service, HospitalIntussusceptionChildEnemaHospitalizationHumansInfantLaparotomyRetrospective Studiesenemaintussusceptionoutpatientsurgery

Identifiers

PMID33158508
PMCPMC7920908
OpenAlexW3092120808

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.