Evidence map›Paper›PMID 33158500›Full record

Observational studyBritish journal of anaesthesia2021

Prone positioning for patients intubated for severe acute respiratory distress syndrome (ARDS) secondary to COVID-19: a retrospective observational cohort study.

Tyler T Weiss, Flor Cerda, J Brady Scott, Ramandeep Kaur, Sarah Sungurlu, Sara H Mirza, Amnah A Alolaiwat, Ramandeep Kaur, Ashley E Augustynovich, Jie Li

2 registry-linked trialsOpen access · bronzeAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in British journal of anaesthesia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 60 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 9 pooled it
14.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04692779 completednot on this map

A Prospective Clinical Study to Explore the Mechanism of Patients' Response to Prone Positioning in ARDS Patients, Including COVID-19

TypeobservationalSponsorRush University Medical CenterRan2021 to 2024Enrolled60ConditionsCovid19, ARDSArmsLung Ultrasound (LUS)
NCT04855162 completednot on this map

Use of Lung Ultrasound in Evaluating Physiological Response to Awake Self Proning

TypeobservationalSponsorRush University Medical CenterRan2021 to 2021Enrolled74ConditionsCovid19
3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 9 syntheses or guidelines pooled it, 142 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Tyler T WeissDepartment of Respiratory Care, Rush University Medical Center, Chicago, IL, USA.
Flor CerdaDepartment of Nursing, Medical Intensive Care Unit, Rush University Medical Center, Chicago, IL, USA.
J Brady ScottDepartment of Respiratory Care, Rush University Medical Center, Chicago, IL, USA; Department of Cardiopulmonary Sciences, Division of Respiratory Care, Rush University, Chicago, IL, USA.
Ramandeep KaurDepartment of Respiratory Care, Rush University Medical Center, Chicago, IL, USA.
Sarah SungurluDepartment of Pulmonary and Critical Care, Rush University Medical Center, Chicago, IL, USA.
Sara H MirzaDepartment of Respiratory Care, Rush University Medical Center, Chicago, IL, USA; Department of Pulmonary and Critical Care, Rush University Medical Center, Chicago, IL, USA.
Amnah A AlolaiwatDepartment of Cardiopulmonary Sciences, Division of Respiratory Care, Rush University, Chicago, IL, USA.
Ramandeep KaurDepartment of Cardiopulmonary Sciences, Division of Respiratory Care, Rush University, Chicago, IL, USA.
Ashley E AugustynovichDepartment of Cardiopulmonary Sciences, Division of Respiratory Care, Rush University, Chicago, IL, USA.
Jie LiDepartment of Respiratory Care, Rush University Medical Center, Chicago, IL, USA; Department of Cardiopulmonary Sciences, Division of Respiratory Care, Rush University, Chicago, IL, USA. Electronic address: Jie_Li@rush.edu.
Rush University · USRush University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe role of repeated prone positioning in intubated subjects with acute respiratory distress syndrome caused by COVID-19 remains unclear.

methodsWe conducted a retrospective observational cohort study of critically ill intubated patients with COVID-19 who were placed in the prone position between March 18, 2020 and March 31, 2020. Exclusion criteria were pregnancy, reintubation, and previous prone positioning at a referring hospital. Patients were followed up until hospital discharge. The primary outcome was oxygenation assessed by partial pressure of oxygen/fraction of inspired oxygen ratio (Pao

resultsForty-two subjects (29 males; age: 59 [52-69] yr) were eligible for analysis. Nine subjects were placed in the prone position only once, with 25 requiring prone positioning on three or more occasions. A total of 31/42 (74%) subjects survived to discharge, with five requiring ECMO; 11/42 (26%) subjects died. After the first prone positioning session, Pao

conclusionPatients with COVID-19 acute respiratory distress syndrome frequently responded to initial prone positioning with improved oxygenation. Subsequent prone positioning in subjects discharged from hospital was associated with greater improvements in oxygenation.

Indexed as

AgedCohort StudiesCOVID-19FemaleFollow-Up StudiesHumansIntubation, IntratrachealMaleMiddle AgedProne PositionRespiratory Distress SyndromeRespiratory MechanicsRetrospective Studiesacute respiratory distress syndrome (ARDS)COVID-19mechanical ventilationoxygenationprone positioning

Identifiers

PMID33158500
PMCPMC7547633
OpenAlexW3092371503

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.