Evidence map›Paper›PMID 33158250›Full record

ArticleMolecules (Basel, Switzerland)2020

Design of Fluorescent Coumarin-Hydroxamic Acid Derivatives as Inhibitors of HDACs: Synthesis, Anti-Proliferative Evaluation and Docking Studies.

Santiago García, Itzel Mercado-Sánchez, Luis Bahena, Yolanda Alcaraz, Marco A García-Revilla, Juvencio Robles, Nancy Santos-Martínez, David Ordaz-Rosado, Rocío García-Becerra, Miguel A Vazquez

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Synthesis andRSC advances · 2026
    Article
  3. Article
  4. Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Santiago GarcíaDepartamento de Química, Universidad de Guanajuato, Guanajuato, Gto. 36050, Mexico.ORCID 0000-0002-1662-2301
Itzel Mercado-SánchezDepartamento de Química, Universidad de Guanajuato, Guanajuato, Gto. 36050, Mexico.
Luis BahenaDepartamento de Química, Universidad de Guanajuato, Guanajuato, Gto. 36050, Mexico.ORCID 0000-0003-2666-6559
Yolanda AlcarazDepartamento de Farmacia, Universidad de Guanajuato, Guanajuato, Gto. 36050, Mexico.
Marco A García-RevillaDepartamento de Química, Universidad de Guanajuato, Guanajuato, Gto. 36050, Mexico.
Juvencio RoblesDepartamento de Farmacia, Universidad de Guanajuato, Guanajuato, Gto. 36050, Mexico.ORCID 0000-0002-8702-5782
Nancy Santos-MartínezDepartamento de Biología de la Reproducción Dr. Carlos Gual Castro, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México 14080, Mexico.
David Ordaz-RosadoDepartamento de Biología de la Reproducción Dr. Carlos Gual Castro, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México 14080, Mexico.
Rocío García-BecerraDepartamento de Biología Molecular y Biotecnología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.
Miguel A VazquezDepartamento de Química, Universidad de Guanajuato, Guanajuato, Gto. 36050, Mexico.ORCID 0000-0002-2240-4669
Universidad de Guanajuato · MXInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MXUniversidad Nacional Autónoma de México · MX

Funding

CONACYT A1-S-27694DAIP-UG 072/2020UG-UAA-CONACyT 299078
6 · The paper itself

Abstract

Coumarin-hydroxamic acid derivatives

Indexed as

Breast NeoplasmsCoumarinsFluorescent DyesHistone Deacetylase InhibitorsHydroxamic AcidsMolecular Docking SimulationProstatic NeoplasmsCell ProliferationDrug Screening Assays, AntitumorFemaleHumansMaleNeoplasm ProteinsPC-3 CellsStructure-Activity RelationshipCoumarinsFluorescent DyesHistone Deacetylase InhibitorsHydroxamic AcidsNeoplasm Proteinscoumarinsdocking analysisfluorescent probegene expressionHDAChydroxamic acids

Identifiers

PMID33158250
PMCPMC7662212
OpenAlexW3097142194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.