Evidence map›Paper›PMID 33158182›Full record

ReviewLife (Basel, Switzerland)2020

Copper-ATSM as a Treatment for ALS: Support from Mutant SOD1 Models and Beyond.

Sara Nikseresht, James B W Hilton, Kai Kysenius, Jeffrey R Liddell, Peter J Crouch

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Cuproptosis and Cu: a new paradigm in cellular death and their role in non-cancerous diseases.Apoptosis : an international journal on programmed cell death · 2024
    Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Copper homeostasis and the ubiquitin proteasome system.Metallomics : integrated biometal science · 2023
    Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Copper, Iron, and Manganese Toxicity in Neuropsychiatric Conditions.International journal of molecular sciences · 2021
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sara NiksereshtDepartment of Pharmacology and Therapeutics, The University of Melbourne, Melbourne, VIC 3010, Australia.
James B W HiltonDepartment of Pharmacology and Therapeutics, The University of Melbourne, Melbourne, VIC 3010, Australia.
Kai KyseniusDepartment of Pharmacology and Therapeutics and Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, VIC 3010, Australia.ORCID 0000-0003-1038-2850
Jeffrey R LiddellDepartment of Pharmacology and Therapeutics, The University of Melbourne, Melbourne, VIC 3010, Australia.ORCID 0000-0002-0798-5338
Peter J CrouchDepartment of Pharmacology and Therapeutics and Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, VIC 3010, Australia.ORCID 0000-0002-7777-4747
The University of Melbourne · AU

Funding

FightMND 04_TRG_2017_CrouchMotor Neurone Disease Australia N/AUniversity of Melbourne N/A
6 · The paper itself

Abstract

The blood-brain barrier permeant, copper-containing compound, Cu

Indexed as

amyotrophic lateral sclerosis (ALS)coppercopper-ATSMCuII(atsm)motor neurone disease (MND)neurodegenerative diseasesporadic

Identifiers

PMID33158182
PMCPMC7694234
OpenAlexW3096749909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.