Evidence map›Paper›PMID 33158164›Full record

ReviewJournal of cardiovascular development and disease2020

The Mesenchymal Cap of the Atrial Septum and Atrial and Atrioventricular Septation.

Ray Deepe, Emily Fitzgerald, Renélyn Wolters, Jenna Drummond, Karen De Guzman, Maurice J B van den Hoff, Andy Wessels

Abstract readReview
In one paragraph

Review in Journal of cardiovascular development and disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Sox9 in the second heart field and the development of the outflow tract; implications for cardiac septation and valve formation.Developmental dynamics : an official publication of the American Association of Anatomists · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Patent Foramen Ovale-A Not So Innocuous Septal Atrial Defect in Adults.Journal of cardiovascular development and disease · 2021
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ray DeepeDepartment of Regenerative Medicine and Cell Biology, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425, USA.
Emily FitzgeraldDepartment of Regenerative Medicine and Cell Biology, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425, USA.
Renélyn WoltersDepartment of Regenerative Medicine and Cell Biology, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425, USA.
Jenna DrummondDepartment of Regenerative Medicine and Cell Biology, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425, USA.
Karen De GuzmanDepartment of Regenerative Medicine and Cell Biology, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425, USA.
Maurice J B van den HoffAmsterdam UMC, Academic Medical Center, Department of Medical Biology, Meibergdreef 15, 1105AZ Amsterdam, The Netherlands.
Andy WesselsDepartment of Regenerative Medicine and Cell Biology, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425, USA.ORCID 0000-0002-3805-9361

Funding

Mechanisms of DMP Development and Atrioventricular SeptationR01HL122906 · NHLBI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI WESSELS, ARNO · 2015 to 2025
$4.3M
NHLBI NIH HHS R01 HL122906NIH HHS R01HL122906
6 · The paper itself

Abstract

In this publication, dedicated to Professor Robert H. Anderson and his contributions to the field of cardiac development, anatomy, and congenital heart disease, we will review some of our earlier collaborative studies. The focus of this paper is on our work on the development of the atrioventricular mesenchymal complex, studies in which Professor Anderson has played a significant role. We will revisit a number of events relevant to atrial and atrioventricular septation and present new data on the development of the mesenchymal cap of the atrial septum, a component of the atrioventricular mesenchymal complex which, thus far, has received only moderate attention.

Indexed as

atrial septumcushiondorsal mesenchymal protrusionmesenchymal capvalve

Identifiers

PMID33158164
PMCPMC7712865

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.