Evidence map›Paper›PMID 33158034›Full record

ArticleAnimals : an open access journal from MDPI2020

Blastocyst-Bearing Sows Display a Dominant Anti-Inflammatory Cytokine Profile Compared to Cyclic Sows at Day 6 of the Cycle.

Inmaculada Parrilla, Cristina A Martinez, Josep M Cambra, Xiomara Lucas, Graça Ferreira-Dias, Heriberto Rodriguez-Martinez, Cristina Cuello, Maria A Gil, Emilio A Martinez

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Exposure ofFrontiers in veterinary science · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Immunological uterine response to pig embryos before and during implantation.Reproduction in domestic animals = Zuchthygiene · 2022
    Review
  9. Seminal Plasma: Relevant for Fertility?International journal of molecular sciences · 2021
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Inmaculada ParrillaFaculty of Veterinary Medicine, International Excellence Campus for Higher Education and Research "Campus Mare Nostrum", University of Murcia, 30071 Murcia, Spain.ORCID 0000-0002-5121-758X
Cristina A MartinezFaculty of Veterinary Medicine, International Excellence Campus for Higher Education and Research "Campus Mare Nostrum", University of Murcia, 30071 Murcia, Spain.ORCID 0000-0001-6811-0191
Josep M CambraFaculty of Veterinary Medicine, International Excellence Campus for Higher Education and Research "Campus Mare Nostrum", University of Murcia, 30071 Murcia, Spain.
Xiomara LucasFaculty of Veterinary Medicine, International Excellence Campus for Higher Education and Research "Campus Mare Nostrum", University of Murcia, 30071 Murcia, Spain.
Graça Ferreira-DiasCIISA-Centre for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medicine, University of Lisbon, 1649-004 Lisbon, Portugal.ORCID 0000-0003-0622-6513
Heriberto Rodriguez-MartinezDepartment of Biomedical & Clinical Sciences (BKV), BKH/Obstetrics & Gynaecology, Faculty of Medicine and Health Sciences, Linköping University, 58183 Linköping, Sweden.ORCID 0000-0002-5194-2124
Cristina CuelloFaculty of Veterinary Medicine, International Excellence Campus for Higher Education and Research "Campus Mare Nostrum", University of Murcia, 30071 Murcia, Spain.ORCID 0000-0002-6202-5946
Maria A GilFaculty of Veterinary Medicine, International Excellence Campus for Higher Education and Research "Campus Mare Nostrum", University of Murcia, 30071 Murcia, Spain.ORCID 0000-0002-6955-7750
Emilio A MartinezFaculty of Veterinary Medicine, International Excellence Campus for Higher Education and Research "Campus Mare Nostrum", University of Murcia, 30071 Murcia, Spain.ORCID 0000-0003-1260-9721
Instituto Murciano de Investigación Biosanitaria · ESLinköping University · SEUniversity of Lisbon · PT

Funding

Fundación Séneca 19892/GERM/15H2020 Marie Skłodowska-Curie Actions 891663Ministerio de Ciencia, Innovación y Universidades RTI2018-093525-B-I00Ministerio de Economía, Industria y Competitividad, Gobierno de España AGL2015-69735-RSvenska Forskningsrådet Formas 2017-00946 and 2019-00288
6 · The paper itself

Abstract

In the context of porcine embryo transfer (ET) technology, understanding the tightly regulated local uterine immune environment is crucial to achieve an adequate interaction between the transferred embryos and the receiving endometrium. However, information is limited on the uterine immune status of cyclic-recipient sows when receiving embryos during ET. The present study postulated that the anti- and proinflammatory cytokine profile 6 days after the onset of estrus differs between endometria from uninseminated cyclic sows and blastocyst-bearing sows. On Day 6 of the cycle, endometrial explants were collected from sows inseminated or not inseminated during the postweaning estrus and cultured for 22 h. The culture medium was then analyzed for the contents of a total of 16 cytokines using Luminex MAP

Indexed as

cytokinesembryo transferendometriumexplantsmaternal immune responsepig

Identifiers

PMID33158034
PMCPMC7692685
OpenAlexW3096702282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.