Evidence map›Paper›PMID 33157989›Full record

ArticleMedicine2020

Predictive value of MEP1A in cancer prognosis: A protocol for systematic review and meta-analysis.

Yong Chen, Fangfang Wu, Li Zhang, Li Du, Xiang Yan

Abstract read
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yong ChenThe First Hospital of Lanzhou University.
Fangfang WuEvidence-Based Nursing Center, School of Nursing, Lanzhou University.
Li ZhangThe Third Ward of Cardiovascular Clinical Medical Center, Affiliated Hospital of Gansu University of Chinese Medicine.
Li DuThe Third People's Hospital of Lanzhou City, Lanzhou, China.
Xiang YanThe First Hospital of Lanzhou University.ORCID 0000-0002-2267-0713

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMeprin is a member of the astaxanthin family; it performs many functions through a wide range of proteolytic enzyme activities during health and disease, including tumors and inflammatory conditions. The purpose of this systematic review was to evaluate the predictive value of MEP1A in tumor prognosis.

methodsA comprehensive search was conducted on PubMed, Cochrane library, and Web of Science Database using a developed search strategy. The Newcastle-Ottawa Scale (NOS) or the Cochrane Collaboration's tool for assessing risk of bias will be used to access the methodological quality of included studies, and GRADE will be applied to evaluate evidence quality of outcomes. All analyses were performed by Stata 15.0.

resultsThe results will systematically summarize and display the currently collected evidence on the predictive value of MEP1A in different tumor prognosis.

conclusionThis study may play a certain role in predicting the prognosis of cancer patients in the future, and may prompt clinicians to make necessary treatment or prevention plans as soon as possible. ETHICS AND COMMUNICATION: It is not necessary because the present systematic review is based on published studies. INPLASY REGISTRATION NUMBER: INPLASY2020100005.

Indexed as

Meta-Analysis as TopicResearch DesignSystematic Reviews as TopicHumansMetalloendopeptidasesNeoplasmsPredictive Value of TestsPrognosisSurvival Ratemeprin AMetalloendopeptidases

Identifiers

PMID33157989
PMCPMC7647559

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.