Evidence map›Paper›PMID 33157516›Full record

ArticleTranslational oncology2021

A higher platelet-to-lymphocyte ratio is prevalent in the presence of circulating tumor microemboli and is a potential prognostic factor for non-metastatic colon cancer.

Emne Ali Abdallah, Virgílio Souza E Silva, Alexcia Camila Braun, Vanessa Alves Gasparini, Bruna Elisa Catin Kupper, Milena Shizue Tariki, José Gabriel Rodriguez Tarazona, Renata Mayumi Takahashi, Samuel Aguiar Júnior, Ludmilla Thomé Domingos Chinen

Open access · goldAbstract read
In one paragraph

Article in Translational oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Emne Ali AbdallahInternational Research Center, A.C. Camargo Cancer Center, 440 Taguá Street, Liberdade, 01508-010 São Paulo, SP, Brazil.
Virgílio Souza E SilvaDepartment of Medical Oncology, A.C. Camargo Cancer Center, São Paulo, Brazil.
Alexcia Camila BraunInternational Research Center, A.C. Camargo Cancer Center, 440 Taguá Street, Liberdade, 01508-010 São Paulo, SP, Brazil.
Vanessa Alves GaspariniInternational Research Center, A.C. Camargo Cancer Center, 440 Taguá Street, Liberdade, 01508-010 São Paulo, SP, Brazil.
Bruna Elisa Catin KupperInternational Research Center, A.C. Camargo Cancer Center, 440 Taguá Street, Liberdade, 01508-010 São Paulo, SP, Brazil.
Milena Shizue TarikiDepartment of Medical Oncology, A.C. Camargo Cancer Center, São Paulo, Brazil.
José Gabriel Rodriguez TarazonaInternational Research Center, A.C. Camargo Cancer Center, 440 Taguá Street, Liberdade, 01508-010 São Paulo, SP, Brazil.
Renata Mayumi TakahashiDepartment of Pelvic Surgery, A.C. Camargo Cancer Center, São Paulo, Brazil.
Samuel Aguiar JúniorDepartment of Pelvic Surgery, A.C. Camargo Cancer Center, São Paulo, Brazil.
Ludmilla Thomé Domingos ChinenInternational Research Center, A.C. Camargo Cancer Center, 440 Taguá Street, Liberdade, 01508-010 São Paulo, SP, Brazil. Electronic address: ludmilla.chinen@accamargo.org.br.
AC Camargo Hospital · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer is a common and often deadly cancer. Circulating tumor cells (CTCs) have been implicated as a potentially valuable prognosis factor. The detection of circulating tumor microemboli (CTM) and of simple blood component parameters that reflect inflammatory status, such as the platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR), may provide information about tumor progression. The aim of this study was to explore the importance of CTCs, CTM, PLR, and NLR prospectively in non-metastatic colon cancer progression. CTCs were enriched using ISET

Indexed as

Circulating tumor cellsCirculating tumor microemboliColon adenocarcinomaLiquid biopsyPlatelet-to-lymphocyte ratio

Identifiers

PMID33157516
PMCPMC7649529
OpenAlexW3097690980

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.