ArticleKidney international2021
Estimation of the glomerular filtration rate in children and young adults by means of the CKD-EPI equation with age-adjusted creatinine values.
Article in Kidney international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Pooled it
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- Examining commonly used equations for estimating the glomerular filtration rate (GFR) in a healthy cohort of children and adolescents.BMC nephrology · 2026Observational
- Establishment of reference intervals for 41 serum biochemical analytes in healthy Chinese children.Practical laboratory medicine · 2026Article
- Which glomerular filtration rate estimation equations should be used in youth with type 1 diabetes?Pediatric nephrology (Berlin, Germany) · 2026Article
- Multi-dimensional sleep patterns predict complications and mortality in chronic kidney disease patients: a prospective study from the UK Biobank.Frontiers in public health · 2026Article
- PopPK and PBPK Models Guide Meropenem Dosing in Critically Ill Children with Augmented Renal Clearance.Pharmaceutics · 2025Article
- Measuring and estimating the GFR in children: state of the art in 2025.Pediatric nephrology (Berlin, Germany) · 2025Review
- An innocent bystander or a predisposing culprit? Kidney injury following pediatric liver transplantation.Pediatric nephrology (Berlin, Germany) · 2025Article
- Switching to the CKD-EPI but Not Modified FAS eGFR Formula Underdetects CKD Among Adolescents and Young Adults in México.Children (Basel, Switzerland) · 2025Article
- Embracing sex-specific differences in engineered kidney models for enhanced biological understanding of kidney function.Biology of sex differences · 2024Review
- Comparison of the prevalence and associated factors of chronic kidney disease diagnosed by serum creatinine or cystatin C among young people living with HIV in Uganda.BMC nephrology · 2024Article
- The evaluation of kidney function estimation during lifestyle intervention in children with overweight and obesity.Pediatric nephrology (Berlin, Germany) · 2024Observational
- Diagnostic approach to rickets: an Endocrine Society of Bengal (ESB) consensus statement.Annals of pediatric endocrinology & metabolism · 2024Article
- Application of the European Kidney Function Consortium Equation to Estimate Glomerular Filtration Rate: A Comparison Study of the CKiD and CKD-EPI Equations Using the Korea National Health and Nutrition Examination Survey (KNHANES 2008-2021).Medicina (Kaunas, Lithuania) · 2024Article
- Extending the cystatin C based EKFC-equation to children - validation results from Europe.Pediatric nephrology (Berlin, Germany) · 2024Article
- Noninvasive Advanced Cardiovascular Magnetic Resonance-Derived Fontan Hemodynamics Are Associated With Reduced Kidney Function But Not Albuminuria.Journal of the American Heart Association · 2024Article
- Podocyte number and glomerulosclerosis indices are associated with the response to therapy for primary focal segmental glomerulosclerosis.Frontiers in medicine · 2024Article
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Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The CKD-EPI creatinine-based estimation equation for glomerular filtration rate (GFR) cannot be used in children, overestimates GFR in young adults, and its combination with the KDIGO recommended pediatric CKiD (Schwartz bedside) equation causes implausible increases in estimated GFR when switching from pediatric to adult care. By establishing sex-specific creatinine growth curves for children and young adults, creatinine levels of children and young adults below age 40 years were adjusted with 40 as assigned age and applied in the CKD-EPI equation. Validation was performed in 4005 children (2-17 years) and 3309 young adults (18-39 years) using metrics based on bias, precision, and accuracy including percentage of estimates within 30% (P
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