ArticleAngewandte Chemie (International ed. in English)2021
Large-Amplitude Conformational Changes in Self-Assembled Multi-Stranded Aromatic Sheets.
Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
5 citing papers in PubMed.
- A protein-foldamer supramolecular synthon for self-assembled hybrid architectures.Nature chemistry · 2026Article
- Programmable Assembly of Multistranded Helices in Water.Nature communications · 2025Article
- Design of an abiotic unimolecular three-helix bundle.Chemical science · 2025Article
- Discrete Stacked Dimers of Aromatic Oligoamide Helices.Angewandte Chemie (International ed. in English) · 2022Article
- Large-Amplitude Conformational Changes in Self-Assembled Multi-Stranded Aromatic Sheets.Angewandte Chemie (International ed. in English) · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The orchestration of ever larger conformational changes is made possible by the development of increasingly complex foldamers. Aromatic sheets, a rare motif in synthetic foldamer structures, have been designed so as to form discrete stacks of intercalated aromatic strands through the self-assembly of two identical subunits. Ion-mobility ESI-MS confirms the formation of compact dimers. X-ray crystallography reveals the existence of two distinct conformational dimeric states that require large changes to interconvert. Molecular dynamics simulation validates the stability of the two conformations and the possibility of their interconversion.
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Registered trials
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