Evidence map›Paper›PMID 33156871›Full record

Trial reportPloS one2020

Performance of a lymphocyte t interferon gamma test (Quantiferon-TB gold in tube) in the diagnosis of active tuberculosis in HIV-infected children.

Bintou Sanogo, Alain Saga Ouermi, Makoura Barro, Anselme Millogo, Ad Bafa Ibrahim Ouattara, Ouédraogo Abdoul Salam, Boubacar Nacro

Open access · goldAbstract readClinical TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Bintou SanogoDepartment of Pediatrics, University Hospital Center Souro Sanou (CHUSS), Bobo-Dioulasso, Burkina Faso.ORCID 0000-0002-6640-8725
Alain Saga OuermiPediatrics Department, Regional Teaching Hospital of Ouahigouya, Ouahigouya, Burkina Faso.
Makoura BarroDepartment of Pediatrics, University Hospital Center Souro Sanou (CHUSS), Bobo-Dioulasso, Burkina Faso.
Anselme MillogoLaboratory of Bacteriology-Virology, University Hospital Center Souro Sanou (CHUSS) Bobo-Dioulasso, Bobo Dioulasso, Burkina Faso.
Ad Bafa Ibrahim OuattaraPediatrics Department, Regional Hospital of Gaoua, Gaoua, Burkina Faso.
Ouédraogo Abdoul SalamLaboratory of Bacteriology-Virology, University Hospital Center Souro Sanou (CHUSS) Bobo-Dioulasso, Bobo Dioulasso, Burkina Faso.
Boubacar NacroDepartment of Pediatrics, University Hospital Center Souro Sanou (CHUSS), Bobo-Dioulasso, Burkina Faso.
Nazi Boni University · BFCentre Hospitalier Universitaire Yalgado Ouédraogo · BF

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEvaluate the performance of QuantiFERON ® -TB Gold In-Tube test (QFT-GIT), to improve the diagnosis of active tuberculosis (TB) in Human Immuno-Deficiency Virus (HIV)-infected children.

methodSensitivity, specificity, Positive Predictive Value (PPV), Negative Predictive Value (NPV) of QFT-GIT were assessed in 58/63 HIV-infected children who were suspected of having TB.

resultsSensitivity of QFT-GIT was 20.69%, specificity 96.55%, PPV/NPV respectively 85.71% and 54.90%.

conclusionQFT-GIT appears to be of little contribution to the diagnosis of active TB in children living with HIV in a TB-endemic country.

Indexed as

AdolescentCambodiaCameroonCD4 Lymphocyte CountChildChild, PreschoolFemaleHIV InfectionsHumansInfantInfant, NewbornInterferon-gamma Release TestsMaleMycobacterium tuberculosisProspective StudiesSensitivity and Specificity

Identifiers

PMID33156871
PMCPMC7647084
OpenAlexW3096364944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.