Evidence map›Paper›PMID 33156829›Full record

ArticlePLoS biology2020

Task-related activity in human visual cortex.

Zvi N Roth, Minyoung Ryoo, Elisha P Merriam

Open access · goldAbstract read
In one paragraph

Article in PLoS biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Brainwide blood volume reflects opposing neural populations.bioRxiv : the preprint server for biology · 2025
    Article
  3. Heterogeneous Effects of Cognitive Arousal on the Contrast Response in Human Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  4. Article
  5. Article
  6. Pupil-Linked Arousal Modulates Precision of Stimulus Representation in Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Zvi N RothLaboratory of Brain and Cognition, National Institute of Mental Health, NIH, Bethesda, Maryland, United States of America.ORCID 0000-0002-2173-1625
Minyoung RyooLaboratory of Brain and Cognition, National Institute of Mental Health, NIH, Bethesda, Maryland, United States of America.ORCID 0000-0002-0873-4119
Elisha P MerriamLaboratory of Brain and Cognition, National Institute of Mental Health, NIH, Bethesda, Maryland, United States of America.ORCID 0000-0003-2787-566X
National Institute of Mental Health · US

Funding

Object, face, body and scene representations in the human brainZIAMH002909 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI BAKER, CHRIS · 2009 to 2025
$25.5M
Intramural NIH HHS ZIA MH002909
6 · The paper itself

Abstract

The brain exhibits widespread endogenous responses in the absence of visual stimuli, even at the earliest stages of visual cortical processing. Such responses have been studied in monkeys using optical imaging with a limited field of view over visual cortex. Here, we used functional MRI (fMRI) in human participants to study the link between arousal and endogenous responses in visual cortex. The response that we observed was tightly entrained to task timing, was spatially extensive, and was independent of visual stimulation. We found that this response follows dynamics similar to that of pupil size and heart rate, suggesting that task-related activity is related to arousal. Finally, we found that higher reward increased response amplitude while decreasing its trial-to-trial variability (i.e., the noise). Computational simulations suggest that increased temporal precision underlies both of these observations. Our findings are consistent with optical imaging studies in monkeys and support the notion that arousal increases precision of neural activity.

Indexed as

ArousalBrain MappingCognitionFemaleHeart RateHumansMagnetic Resonance ImagingMaleModels, NeurologicalNeurovascular CouplingPhotic StimulationRewardTask Performance and AnalysisVisual CortexVisual Perception

Identifiers

PMID33156829
PMCPMC7673548
OpenAlexW3097159416

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.